Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma
Published 2019 View Full Article
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Title
Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-04-11
DOI
10.1038/s41467-019-09255-1
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Note: Only part of the references are listed.- Immune checkpoint blockade in esophageal squamous cell carcinoma: is it ready for prime time?
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- (2017) Nene N. Kalu et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
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- (2017) Xi Liu et al. GASTROENTEROLOGY
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- (2017) Xi-Xi Chen et al. Nature Communications
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- (2017) Jin Zhou et al. Nature Communications
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- (2017) Alexandre Reuben et al. Cancer Discovery
- Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma
- (2016) Caixia Cheng et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer
- (2016) M. L. Telli et al. CLINICAL CANCER RESEARCH
- Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population
- (2016) Genta Sawada et al. GASTROENTEROLOGY
- MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets
- (2016) Sudhir Kumar et al. MOLECULAR BIOLOGY AND EVOLUTION
- Analysis of protein-coding genetic variation in 60,706 humans
- (2016) Monkol Lek et al. NATURE
- Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma
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- NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets
- (2016) Morten Nielsen et al. Genome Medicine
- Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma
- (2016) Caixia Cheng et al. GigaScience
- Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma
- (2015) Ling Zhang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- High response rates to neoadjuvant platinum-based therapy in ovarian cancer patients carrying germ-line BRCA mutation
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- IMonitor: A Robust Pipeline for TCR and BCR Repertoire Analysis
- (2015) Wei Zhang et al. GENETICS
- Oncotator: Cancer Variant Annotation Tool
- (2015) Alex H. Ramos et al. HUMAN MUTATION
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- (2015) Sachet A Shukla et al. NATURE BIOTECHNOLOGY
- Clock-like mutational processes in human somatic cells
- (2015) Ludmil B Alexandrov et al. NATURE GENETICS
- Personalized targeted therapy for esophageal squamous cell carcinoma
- (2015) Xiaozheng Kang WORLD JOURNAL OF GASTROENTEROLOGY
- IMonitor: A Robust Pipeline for TCR and BCR Repertoire Analysis
- (2015) Wei Zhang et al. GENETICS
- Targeting genetic lesions in esophageal cancer
- (2014) De-Chen Lin et al. CELL CYCLE
- Identification of genomic alterations in oesophageal squamous cell cancer
- (2014) Yongmei Song et al. NATURE
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- (2014) Michael S. Lawrence et al. NATURE
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- (2014) Andy Rimmer et al. NATURE GENETICS
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- (2014) Yi-Bo Gao et al. NATURE GENETICS
- Genomic and molecular characterization of esophageal squamous cell carcinoma
- (2014) De-Chen Lin et al. NATURE GENETICS
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- (2014) J. Zhang et al. SCIENCE
- Squamous Dysplasia--The Precursor Lesion for Esophageal Squamous Cell Carcinoma
- (2013) P. R. Taylor et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- High-throughput sequencing of T-cell receptors reveals a homogeneous repertoire of tumour-infiltrating lymphocytes in ovarian cancer
- (2013) Ryan O Emerson et al. JOURNAL OF PATHOLOGY
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- (2013) Ludmil B. Alexandrov et al. NATURE
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- (2009) Prateek Kumar et al. Nature Protocols
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
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