A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-04-23
DOI
10.1038/s41467-019-09880-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box
- (2018) R. S. Jumani et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium
- (2018) Alexander T. Chao et al. ACS Infectious Diseases
- New developments in anti-malarial target candidate and product profiles
- (2017) Jeremy N. Burrows et al. MALARIA JOURNAL
- Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
- (2017) Vitul Jain et al. STRUCTURE
- A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis
- (2017) Melissa S. Love et al. PLoS Neglected Tropical Diseases
- Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study
- (2016) Jie Liu et al. LANCET
- Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
- (2016) Theo Vos et al. LANCET
- Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
- (2016) Nobutaka Kato et al. NATURE
- Cryptosporidiosis Drug Discovery: Opportunities and Challenges
- (2016) Ujjini H. Manjunatha et al. ACS Infectious Diseases
- A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
- (2015) William Checkley et al. LANCET INFECTIOUS DISEASES
- Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum
- (2015) Sumiti Vinayak et al. NATURE
- Hit and lead criteria in drug discovery for infectious diseases of the developing world
- (2015) Kei Katsuno et al. NATURE REVIEWS DRUG DISCOVERY
- A Proposed Target Product Profile and Developmental Cascade for New Cryptosporidiosis Treatments
- (2015) Christopher D. Huston et al. PLoS Neglected Tropical Diseases
- Oleylphosphocholine (OlPC) arrests Cryptosporidium parvum growth in vitro and prevents lethal infection in interferon gamma receptor knock-out mice
- (2015) Karine Sonzogni-Desautels et al. Frontiers in Microbiology
- Identification of Cryptosporidium parvum Active Chemical Series by Repurposing the Open Access Malaria Box
- (2014) K. Bessoff et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ward’s Hierarchical Agglomerative Clustering Method: Which Algorithms Implement Ward’s Criterion?
- (2014) Fionn Murtagh et al. JOURNAL OF CLASSIFICATION
- HIV Treatments Reduce Malaria Liver Stage Burden in a Non-Human Primate Model of Malaria Infection at Clinically Relevant Concentrations In Vivo
- (2014) Charlotte V. Hobbs et al. PLoS One
- Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis
- (2013) Suresh Kumar Gorla et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Cysteine Protease Inhibitor Rescues Mice from a Lethal Cryptosporidium parvum Infection
- (2013) Momar Ndao et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Drug Repurposing Screen Reveals FDA-Approved Inhibitors of Human HMG-CoA Reductase and Isoprenoid Synthesis That Block Cryptosporidium parvum Growth
- (2013) Kovi Bessoff et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Novel Calcium-Dependent Protein Kinase Inhibitor as a Lead Compound for Treating Cryptosporidiosis
- (2013) Alejandro Castellanos-Gonzalez et al. JOURNAL OF INFECTIOUS DISEASES
- Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
- (2013) Karen L Kotloff et al. LANCET
- Burden of disease from cryptosporidiosis
- (2012) Debbie-Ann T. Shirley et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Selective and Potent Urea Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
- (2012) Suresh Kumar Gorla et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Cryptosporidium Parvum Transcriptome during In Vitro Development
- (2012) Mary J. Mauzy et al. PLoS One
- Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites
- (2012) Godfree Mlambo et al. PLoS One
- Selective Inhibitors of Methionyl-tRNA Synthetase Have Potent Activity against Trypanosoma brucei Infection in Mice
- (2011) Sayaka Shibata et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Targeted Disruption of TgPhIL1 in Toxoplasma gondii Results in Altered Parasite Morphology and Fitness
- (2011) Whittney Dotzler Barkhuff et al. PLoS One
- High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial
- (2009) Beatrice Amadi et al. BMC INFECTIOUS DISEASES
- A chemical method for fast and sensitive detection of DNA synthesis in vivo
- (2008) A. Salic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now