Drug Repurposing Screen Reveals FDA-Approved Inhibitors of Human HMG-CoA Reductase and Isoprenoid Synthesis That Block Cryptosporidium parvum Growth

Cryptosporidium parvumscavenges LDL-derived cholesterol and micellar cholesterol internalized into enterocytes

(2013) Karen Ehrenman et al.   CELLULAR MICROBIOLOGY

Novel Aspects of Mevalonate Pathway Inhibitors as Antitumor Agents

(2012) M. Thurnher et al.   CLINICAL CANCER RESEARCH

Pitavastatin: An overview

(2011) Yasushi Saito   ATHEROSCLEROSIS SUPPLEMENTS

Efficacy of statins for primary prevention in people at low cardiovascular risk: a meta-analysis

(2011) M. Tonelli et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance inToxoplasma gondii

(2011) Sethu C. Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

Five Questions about Non-Mevalonate Isoprenoid Biosynthesis

(2011) Audrey R. Odom   PLoS Pathogens

Plasmodium salvages cholesterol internalized by LDL and synthesized de novo in the liver

(2010) Mehdi Labaied et al.   CELLULAR MICROBIOLOGY

Prodrug Activation byCryptosporidiumThymidine Kinase

(2010) Xin E. Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

A Screening Pipeline for Antiparasitic Agents Targeting Cryptosporidium Inosine Monophosphate Dehydrogenase

(2010) Lisa Sharling et al.   PLoS Neglected Tropical Diseases

EuPathDB: a portal to eukaryotic pathogen databases

(2009) Cristina Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

Targeting a Uniquely Nonspecific Prenyl Synthase with Bisphosphonates to Combat Cryptosporidiosis

(2008) Jennifer D. Artz et al.   CHEMISTRY & BIOLOGY

Statins inhibit Toxoplasma gondii multiplication in macrophages in vitro

(2008) Erika Cortez et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS