Monomethyltransferase SET8 facilitates hepatocellular carcinoma growth by enhancing aerobic glycolysis

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PDSS2 deficiency induces hepatocarcinogenesis by decreasing mitochondrial respiration and reprogramming glucose metabolism

(2018) Yan Li et al.   CANCER RESEARCH

Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial–Mesenchymal Transition

(2018) Fanyang Kong et al.   CLINICAL CANCER RESEARCH

Krüppel-like factor 4 (KLF4): What we currently know

(2017) Amr M. Ghaleb et al.   GENE

Loss of KLF4 and consequential downregulation of Smad7 exacerbate oncogenic TGF-β signaling in and promote progression of hepatocellular carcinoma

(2017) H Sun et al.   ONCOGENE

KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling

(2017) Yongzheng Ma et al.   ONCOLOGY REPORTS

Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions

(2017) Kostas C. Nikolaou et al.   Cell Reports

MiR-502/SET8 regulatory circuit in pathobiology of breast cancer

(2016) Ben Liu et al.   CANCER LETTERS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway

(2016) Y Shen et al.   LEUKEMIA

The emerging role of lysine methyltransferase SETD8 in human diseases

(2016) Ciro Milite et al.   Clinical Epigenetics

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

SET8 expression is associated with overall survival in gastric cancer

(2015) X.L. Shi et al.   GENETICS AND MOLECULAR RESEARCH

SET8 induces epithelial-mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1

(2015) LIEJUN HOU et al.   Molecular Medicine Reports

Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis

(2015) Dong Hu et al.   Nature Communications

Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity

(2014) Rommel A. Mathias et al.   CELL

A Novel KLF4/LDHA Signaling Pathway Regulates Aerobic Glycolysis in and Progression of Pancreatic Cancer

(2014) M. Shi et al.   CLINICAL CANCER RESEARCH

The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail ‘histone code’ and Riz1 tumor suppressor function

(2014) Lauren M. Congdon et al.   NUCLEIC ACIDS RESEARCH

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

(2013) Seung Min Jeong et al.   CANCER CELL

Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification

(2013) Diren Beyoğlu et al.   HEPATOLOGY

Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis

(2013) Gurpreet Kaur Dhami et al.   MOLECULAR CELL

SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase

(2013) Gaëlle Laurent et al.   MOLECULAR CELL

Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression

(2012) M. Takawa et al.   CANCER RESEARCH

PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription

(2012) D. B. Beck et al.   GENES & DEVELOPMENT

Krüppel-Like Factor 4, a Tumor Suppressor in Hepatocellular Carcinoma Cells Reverts Epithelial Mesenchymal Transition by Suppressing Slug Expression

(2012) Ze-Shiang Lin et al.   PLoS One

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail

(2011) Yinliang Yin et al.   CELL CYCLE

A new regulator of the cell cycle

(2011) Shumin Wu et al.   CELL CYCLE

SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities

(2011) Fen Yang et al.   EMBO JOURNAL

A polymorphism at the miR-502 binding site in the 3′-untranslated region of the histone methyltransferase SET8 is associated with hepatocellular carcinoma outcome

(2011) Zhanjun Guo et al.   INTERNATIONAL JOURNAL OF CANCER

Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion

(2011) F Yu et al.   ONCOGENE

Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation

(2011) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Krüppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis

(2010) Yi-Ju Chen et al.   CANCER BIOLOGY & THERAPY

PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression

(2010) Lauren M. Congdon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

The Prognostic Value of F-18 Fluorodeoxyglucose Bone Marrow Uptake in Patients With Recent Diagnosis of Multiple Myeloma

(2009) Massimo Castellani et al.   CLINICAL NUCLEAR MEDICINE

Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development

(2009) H. Oda et al.   MOLECULAR AND CELLULAR BIOLOGY

Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells

(2008) Paul M Evans et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic Stability

(2008) Sabrina I. Houston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY