Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools

Molecular Mechanism and Evolution of Nuclear Pre-mRNA and Group II Intron Splicing: Insights from Cryo-Electron Microscopy Structures

(2018) Wojciech P. Galej et al.   CHEMICAL REVIEWS

A Highly Proliferative Group IIC Intron from Geobacillus stearothermophilus Reveals New Features of Group II Intron Mobility and Splicing

(2018) Georg Mohr et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM structure of substrate-bound human telomerase holoenzyme

(2018) Thi Hoang Duong Nguyen et al.   NATURE

Structural accommodations accompanying splicing of a group II intron RNP

(2018) Xiaolong Dong et al.   NUCLEIC ACIDS RESEARCH

Simultaneous sequencing of coding and noncoding RNA reveals a human transcriptome dominated by a small number of highly expressed noncoding genes

(2018) Vincent Boivin et al.   RNA

The alternative sigma factor σB plays a crucial role in adaptive strategies of Clostridium difficile during gut infection

(2017) Nicolas Kint et al.   ENVIRONMENTAL MICROBIOLOGY

The Spliceosome: A Protein-Directed Metalloribozyme

(2017) Yigong Shi   JOURNAL OF MOLECULAR BIOLOGY

Base-Resolution Mapping Reveals Distinct m 1 A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts

(2017) Xiaoyu Li et al.   MOLECULAR CELL

Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications

(2017) Jennifer L. Stamos et al.   MOLECULAR CELL

The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution

(2017) Modi Safra et al.   NATURE

Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors

(2017) Ely B Porter et al.   Nature Chemical Biology

Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine

(2017) Sebastian M Fica et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Determination of tRNA aminoacylation levels by high-throughput sequencing

(2017) Molly E. Evans et al.   NUCLEIC ACIDS RESEARCH

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

(2017) Matthew J. Shurtleff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ultraprocessive, accurate reverse transcriptase encoded by a metazoan group II intron

(2017) Chen Zhao et al.   RNA

Mobile Group II Introns as Ancestral Eukaryotic Elements

(2017) Olga Novikova et al.   TRENDS IN GENETICS

Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine

(2017) Sebastian M Fica et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching

(2017) Douglas C. Wu et al.   Scientific Reports

Roles of three AbrBs in regulating two-phase Clostridium acetobutylicum fermentation

(2016) Qiong Xue et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Staphylococcus aureus β-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis and Sepsis

(2016) Alfa Herrera et al.   BIOCHEMISTRY

Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin

(2016) Matthew W. Snyder et al.   CELL

Codon identity regulates mRNA stability and translation efficiency during the maternal‐to‐zygotic transition

(2016) Ariel A Bazzini et al.   EMBO JOURNAL

Host innate inflammatory factors and staphylococcal protein A influence the duration of human Staphylococcus aureus nasal carriage

(2016) A L Cole et al.   Mucosal Immunology

DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo

(2016) Meghan Zubradt et al.   NATURE METHODS

irCLIP platform for efficient characterization of protein–RNA interactions

(2016) Brian J Zarnegar et al.   NATURE METHODS

Reverse transcriptases lend a hand in splicing catalysis

(2016) Joseph A Piccirilli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a group II intron in complex with its reverse transcriptase

(2016) Guosheng Qu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution

(2016) Chen Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Forks in the tracks: Group II introns, spliceosomes, telomeres and beyond

(2016) Rajendra Kumar Agrawal et al.   RNA Biology

tRNA base methylation identification and quantification via high-throughput sequencing

(2016) Wesley C. Clark et al.   RNA

RNA-seq of human reference RNA samples using a thermostable group II intron reverse transcriptase

(2016) Ryan M. Nottingham et al.   RNA

Crystal structures of a group II intron lariat primed for reverse splicing

(2016) M. Costa et al.   SCIENCE

Protective efficacy afforded by live Pasteurella multocida vaccines in chickens is independent of lipopolysaccharide outer core structure

(2016) Marina Harper et al.   VACCINE

Reverse transcriptases lend a hand in splicing catalysis

(2016) Joseph A Piccirilli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a group II intron in complex with its reverse transcriptase

(2016) Guosheng Qu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution

(2016) Chen Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Elucidating the contributions of multiple aldehyde/alcohol dehydrogenases to butanol and ethanol production in Clostridium acetobutylicum

(2016) Zongjie Dai et al.   Scientific Reports

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments

(2015) Kun Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptases

(2015) Yidan Qin et al.   RNA

Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains

(2015) P. S. Shen et al.   SCIENCE

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions

(2015) J. Jiang et al.   SCIENCE

Structure of a yeast spliceosome at 3.6-angstrom resolution

(2015) Chuangye Yan et al.   SCIENCE

Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation

(2015) David M. Truong et al.   PLoS Genetics

The contribution of cellulosomal scaffoldins to cellulose hydrolysis by Clostridium thermocellum analyzed by using thermotargetrons

(2014) Wei Hong et al.   Biotechnology for Biofuels

Crystal structure of a eukaryotic group II intron lariat

(2014) Aaron R. Robart et al.   NATURE

Quaternary arrangement of an active, native group II intron ribonucleoprotein complex revealed by small-angle X-ray scattering

(2014) Kushol Gupta et al.   NUCLEIC ACIDS RESEARCH

Site-Specific, Insertional Inactivation of incA in Chlamydia trachomatis Using a Group II Intron

(2014) Cayla M. Johnson et al.   PLoS One

Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

(2014) G. E. Katibah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of the computer-retargeted group II intron RmInt1 ofSinorhizobium melilotifor gene targeting

(2014) Fernando M García-Rodríguez et al.   RNA Biology

Interaction between Conjugative and Retrotransposable Elements in Horizontal Gene Transfer

(2014) Olga Novikova et al.   PLoS Genetics

Biotechnological applications of mobile group II introns and their reverse transcriptases: gene targeting, RNA-seq, and non-coding RNA analysis

(2014) Peter J Enyeart et al.   Mobile DNA

Generalized bacterial genome editing using mobile group II introns and Cre-lox

(2013) P. J. Enyeart et al.   Molecular Systems Biology

A Targetron System for Gene Targeting in Thermophiles and Its Application in Clostridium thermocellum

(2013) Georg Mohr et al.   PLoS One

Thermostable group II intron reverse transcriptase fusion proteins and their use in cDNA synthesis and next-generation RNA sequencing

(2013) S. Mohr et al.   RNA

Mobile element biology: new possibilities with high-throughput sequencing

(2013) Jinchuan Xing et al.   TRENDS IN GENETICS

Visualizing Group II Intron Catalysis through the Stages of Splicing

(2012) Marco Marcia et al.   CELL

Methicillin-resistantStaphylococcus aureus(MRSA) Pyruvate Kinase as a Target for Bis-indole Alkaloids with Antibacterial Activities

(2011) Roya Zoraghi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic identification of potential RNA-binding regions in a group II intron-encoded reverse transcriptase

(2010) S.-Q. Gu et al.   RNA

Group II Introns: Mobile Ribozymes that Invade DNA

(2010) A. M. Lambowitz et al.   Cold Spring Harbor Perspectives in Biology

Identification of migR, a Regulatory Element of the Francisella tularensis Live Vaccine Strain iglABCD Virulence Operon Required for Normal Replication and Trafficking in Macrophages

(2009) B. W. Buchan et al.   INFECTION AND IMMUNITY

Global Regulators Orchestrate Group II Intron Retromobility

(2009) Colin J. Coros et al.   MOLECULAR CELL

EcI5, a group IIB intron with high retrohoming frequency: DNA target site recognition and use in gene targeting

(2009) F. Zhuang et al.   RNA

Group II Intron-Based Gene Targeting Reactions in Eukaryotes

(2008) Marta Mastroianni et al.   PLoS One

A mutant screen reveals RNase E as a silencer of group II intron retromobility in Escherichia coli

(2008) C. J. Coros et al.   RNA

Crystal Structure of a Self-Spliced Group II Intron

(2008) N. Toor et al.   SCIENCE

Retrotransposition of the Ll.LtrB group II intron proceeds predominantly via reverse splicing into DNA targets

(2003) Kenji Ichiyanagi et al.   MOLECULAR MICROBIOLOGY