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Title
Islet inflammation in type 2 diabetes
Authors
Keywords
Islet inflammation, Type 2 diabetes, IL-1β, Insulin, Cytokines, β-Cell
Journal
Seminars in Immunopathology
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-04-16
DOI
10.1007/s00281-019-00745-4
References
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Note: Only part of the references are listed.- RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity
- (2018) Andisheh Abedini et al. JOURNAL OF CLINICAL INVESTIGATION
- Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells
- (2018) Anping Song et al. Scientific Reports
- β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion
- (2018) Marianne Böni-Schnetzler et al. Cell Reports
- Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled?
- (2018) Yue J. Wang et al. Cell Metabolism
- Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
- (2018) Wei Ying et al. Cell Metabolism
- Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production
- (2017) Elise Dalmas et al. IMMUNITY
- The islet-resident macrophage is in an inflammatory state and senses microbial products in blood
- (2017) Stephen T. Ferris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets
- (2017) Queenie Hui et al. Molecular Metabolism
- The Role of Inflammation in β-cell Dedifferentiation
- (2017) Thierry M. Nordmann et al. Scientific Reports
- RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes
- (2016) Yurong Xin et al. Cell Metabolism
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
- (2016) Åsa Segerstolpe et al. Cell Metabolism
- Single-Cell Transcriptomics of the Human Endocrine Pancreas
- (2016) Yue J. Wang et al. DIABETES
- Insulitis in human diabetes: a histological evaluation of donor pancreases
- (2016) Marcus Lundberg et al. DIABETOLOGIA
- Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates
- (2016) Clara Westwell-Roper et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mast cells infiltrate pancreatic islets in human type 1 diabetes
- (2015) Luisa Martino et al. DIABETOLOGIA
- The pancreas anatomy conditions the origin and properties of resident macrophages
- (2015) Boris Calderon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications
- (2015) Christian Herder et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Islet amyloid with macrophage migration correlates with augmented β-cell deficits in type 2 diabetic patients
- (2014) Kosuke Kamata et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression
- (2014) Christopher Benner et al. BMC GENOMICS
- Islet Microenvironment, Modulated by Vascular Endothelial Growth Factor-A Signaling, Promotes β Cell Regeneration
- (2014) Marcela Brissova et al. Cell Metabolism
- Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes
- (2014) Teresa Rodriguez-Calvo et al. DIABETES
- Angiotensin II Induces Interleukin-1β–Mediated Islet Inflammation and β-Cell Dysfunction Independently of Vasoconstrictive Effects
- (2014) Nadine S. Sauter et al. DIABETES
- TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6
- (2014) Dominika Nackiewicz et al. DIABETOLOGIA
- Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes
- (2014) Matthew J. Butcher et al. DIABETOLOGIA
- IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice
- (2014) Clara Y. Westwell-Roper et al. DIABETOLOGIA
- Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice
- (2014) Daniel T. Meier et al. DIABETOLOGIA
- Transplantation of mesenchymal stem cells recruits trophic macrophages to induce pancreatic beta cell regeneration in diabetic mice
- (2014) Xiaocang Cao et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
- (2014) Sumaira Z Hasnain et al. NATURE MEDICINE
- M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7
- (2014) Xiangwei Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammation in Obesity and Diabetes: Islet Dysfunction and Therapeutic Opportunity
- (2013) Marc Y. Donath et al. Cell Metabolism
- Resident Macrophages Mediate Islet Amyloid Polypeptide–Induced Islet IL-1β Production and β-Cell Dysfunction
- (2013) Clara Y. Westwell-Roper et al. DIABETES
- The diagnosis of insulitis in human type 1 diabetes
- (2013) M. L. Campbell-Thompson et al. DIABETOLOGIA
- Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization
- (2013) H. Cucak et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
- (2013) Steven E Kahn et al. LANCET
- Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
- (2013) Tony Jourdan et al. NATURE MEDICINE
- Secreted Frizzled-Related Protein 4 Reduces Insulin Secretion and Is Overexpressed in Type 2 Diabetes
- (2012) Taman Mahdi et al. Cell Metabolism
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- (2012) Christine M. Oslowski et al. Cell Metabolism
- Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation
- (2012) Kosei Eguchi et al. Cell Metabolism
- Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide
- (2012) Y. J. Park et al. DIABETOLOGIA
- Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin–proteasome system in pancreatic beta cell dysfunction
- (2012) Marco Bugliani et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture
- (2012) Sarita Negi et al. PLoS One
- β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition
- (2011) Catherine A. Jurgens et al. AMERICAN JOURNAL OF PATHOLOGY
- β-Cell evolution: How the pancreas borrowed from the brain
- (2011) Margot E. Arntfield et al. BIOESSAYS
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- (2011) Yun-Hee Youm et al. ENDOCRINOLOGY
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- Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
- (2011) Helga Ellingsgaard et al. NATURE MEDICINE
- Altered Islet Composition and Disproportionate Loss of Large Islets in Patients with Type 2 Diabetes
- (2011) German Kilimnik et al. PLoS One
- Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
- (2010) J. A. Ehses et al. DIABETOLOGIA
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- (2010) M. Igoillo-Esteve et al. DIABETOLOGIA
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- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- Islet-associated macrophages in type 2 diabetes
- (2009) S. J. Richardson et al. DIABETOLOGIA
- Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I
- (2009) Marianne Böni-Schnetzler et al. ENDOCRINOLOGY
- IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
- (2009) J. A. Ehses et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
- The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia
- (2008) Nadine S. Sauter et al. ENDOCRINOLOGY
- Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation
- (2008) Marianne Böni-Schnetzler et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data
- (2008) Rebecca J Brown et al. PEDIATRIC DIABETES
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