Oleandrin sensitizes human osteosarcoma cells to cisplatin by preventing degradation of the copper transporter 1

Cross Talk Between Autophagy and Apoptosis Contributes to ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death

(2018) Guanping He et al.   Advanced Healthcare Materials

The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells

(2017) Stefano Garofalo et al.   JOURNAL OF NEUROSCIENCE

Plant-derived cardiac glycosides: Role in heart ailments and cancer management

(2016) Seema Patel   BIOMEDICINE & PHARMACOTHERAPY

The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy

(2016) Marco Napoli et al.   BRITISH JOURNAL OF CANCER

Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain

(2016) Helena Öhrvik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pharmacogenomics of osteosarcoma

(2016) M Serra et al.   PHARMACOGENOMICS JOURNAL

Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells

(2016) Qingxi Yue et al.   PLoS One

β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1

(2016) Xiaoqiang Li et al.   Scientific Reports

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy

(2015) Helen HW Chen et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inhibition of oleandrin on the proliferation and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway

(2015) Yunlong Ma et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Paradigms of protein degradation by the proteasome

(2014) Tomonao Inobe et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway

(2014) Yong Pan et al.   INVESTIGATIONAL NEW DRUGS

Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer

(2014) Eric S. Kim et al.   LUNG CANCER

Osteosarcoma treatment – Where do we stand? A state of the art review

(2013) Anja Luetke et al.   CANCER TREATMENT REVIEWS

A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment

(2013) Chelsea D. Landon et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

A Hydroalcoholic Extract from the Leaves of Nerium oleander Inhibits Glycolysis and Induces Selective Killing of Lung Cancer Cells

(2013) José Calderón-Montaño et al.   PLANTA MEDICA

Anvirzel™ in combination with cisplatin in breast, colon, lung, prostate, melanoma and pancreatic cancer cell lines

(2013) Panagiotis Apostolou et al.   BMC Pharmacology & Toxicology

Tissue Platinum Concentration and Tumor Response in Non–Small-Cell Lung Cancer

(2012) Eric S. Kim et al.   JOURNAL OF CLINICAL ONCOLOGY

MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines

(2011) Hege O Ohnstad et al.   BMC CANCER

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator

(2010) Seiko Ishida et al.   CANCER CELL

Enhanced Delivery of Cisplatin to Intraperitoneal Ovarian Carcinomas Mediated by the Effects of Bortezomib on the Human Copper Transporter 1

(2009) D. D. Jandial et al.   CLINICAL CANCER RESEARCH

Human Copper Transporter 1 LackingO-Linked Glycosylation Is Proteolytically Cleaved in a Rab9-positive Endosomal Compartment

(2009) Edward B. Maryon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytotoxic Effects of Cardiac Glycosides in Colon Cancer Cells, Alone and in Combination with Standard Chemotherapeutic Drugs

(2009) Jenny Felth et al.   JOURNAL OF NATURAL PRODUCTS

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY