Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility

CABS-flex 2.0: a web server for fast simulations of flexibility of protein structures

(2018) Aleksander Kuriata et al.   NUCLEIC ACIDS RESEARCH

CABS-flex standalone: a simulation environment for fast modeling of protein flexibility

(2018) Mateusz Kurcinski et al.   BIOINFORMATICS

Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility

(2018) Marcos Gil-Garcia et al.   MOLECULAR PHARMACEUTICS

Safety and Efficacy of Bevacizumab Plus Standard-of-Care Treatment Beyond Disease Progression in Patients With Advanced Non–Small Cell Lung Cancer

(2018) Cesare Gridelli et al.   JAMA Oncology

The proteinopathy of D169G and K263E mutants at the RNA Recognition Motif (RRM) domain of tar DNA-binding protein (tdp43) causing neurological disorders: A computational study

(2017) Vishwambhar Vishnu Bhandare et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Driving Forces for Nonnative Protein Aggregation and Approaches to Predict Aggregation-Prone Regions

(2017) Gulsum Meric et al.   Annual Review of Chemical and Biomolecular Engineering

Putative alternative functions of human stefin B (cystatin B): binding to amyloid-beta, membranes, and copper

(2016) Eva Žerovnik   JOURNAL OF MOLECULAR RECOGNITION

Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for “Second Generation” Therapeutic Application

(2016) Xue Xia et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Structural diversity in a human antibody germline library

(2016) Alexey Teplyakov et al.   mAbs

Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis

(2016) Pablo Pulido et al.   PLoS Genetics

Molecular dynamics simulations and docking enable to explore the biophysical factors controlling the yields of engineered nanobodies

(2016) Miguel A. Soler et al.   Scientific Reports

The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility

(2015) Pietro Sormanni et al.   JOURNAL OF MOLECULAR BIOLOGY

Rational design of therapeutic mAbs against aggregation through protein engineering and incorporation of glycosylation motifs applied to bevacizumab

(2015) Fabienne Courtois et al.   mAbs

AGGRESCAN3D (A3D): server for prediction of aggregation properties of protein structures

(2015) Rafael Zambrano et al.   NUCLEIC ACIDS RESEARCH

CABS-flex predictions of protein flexibility compared with NMR ensembles

(2014) Michal Jamroz et al.   BIOINFORMATICS

Capability measurement of size-exclusion chromatography with a light-scattering detection method in a stability study of bevacizumab using the process capability indices

(2014) Alexis Oliva et al.   JOURNAL OF CHROMATOGRAPHY A

Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold

(2014) J. M. Perchiacca et al.   PROTEIN ENGINEERING DESIGN & SELECTION

CABS-flex: server for fast simulation of protein structure fluctuations

(2013) Michal Jamroz et al.   NUCLEIC ACIDS RESEARCH

Proteins behaving badly: emerging technologies in profiling biopharmaceutical aggregation

(2013) Zahra Hamrang et al.   TRENDS IN BIOTECHNOLOGY

Protein aggregation: Mechanisms and functional consequences

(2012) Gaetano Invernizzi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Consistent View of Protein Fluctuations from All-Atom Molecular Dynamics and Coarse-Grained Dynamics with Knowledge-Based Force-Field

(2012) Michal Jamroz et al.   Journal of Chemical Theory and Computation

General strategy for the generation of human antibody variable domains with increased aggregation resistance

(2012) K. Dudgeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the role of the thermodynamic and kinetic stabilities of SH3 domains on their aggregation inside bacteria

(2010) Virginia Castillo et al.   PROTEOMICS

Structural Determinants of Protein Evolution Are Context-Sensitive at the Residue Level

(2009) E. A. Franzosa et al.   MOLECULAR BIOLOGY AND EVOLUTION

The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate With Their Conformational Stability: The SH3 Case

(2008) Alba Espargaró et al.   JOURNAL OF MOLECULAR BIOLOGY