A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

Targeting expression to megakaryocytes and platelets by lineage-specific lentiviral vectors

(2017) L. J. Latorre-Rey et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss

(2016) S. Stritt et al.   BLOOD

Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes

(2016) A. Antkowiak et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets

(2015) A. J. Begonja et al.   BLOOD

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

(2015) Satoshi Nishimura et al.   JOURNAL OF CELL BIOLOGY

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

(2015) Zane S. Kaplan et al.   Nature Communications

The Cdc42 Guanine Nucleotide Exchange Factor FGD6 Coordinates Cell Polarity and Endosomal Membrane Recycling in Osteoclasts

(2014) Charlotte Steenblock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Congenital platelet disorders and understanding of platelet function

(2013) Alan T. Nurden et al.   BRITISH JOURNAL OF HAEMATOLOGY

Growth Factor Receptor–Bound Protein 2 Contributes to (Hem)Immunoreceptor Tyrosine-Based Activation Motif–Mediated Signaling in Platelets

(2013) Sebastian Dütting et al.   CIRCULATION RESEARCH

The incredible journey: From megakaryocyte development to platelet formation

(2013) Kellie R. Machlus et al.   JOURNAL OF CELL BIOLOGY

Phenotypical Analysis of Atypical PKCs In Vivo Function Display a Compensatory System at Mouse Embryonic Day 7.5

(2013) Sebastian Seidl et al.   PLoS One

Platelets in Lung Biology

(2012) Andrew S. Weyrich et al.   Annual Review of Physiology

Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD

(2012) C. Leon et al.   BLOOD

VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice

(2012) S. C. Pitchford et al.   BLOOD

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

(2012) Lin Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GPIb  regulates platelet size by controlling the subcellular localization of filamin

(2011) T. Kanaji et al.   BLOOD

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

(2011) A. Jurak Begonja et al.   BLOOD

Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

(2011) I. Pleines et al.   BLOOD

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome

(2011) P. Nurden et al.   BLOOD

Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

(2010) I. Pleines et al.   BLOOD

Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome

(2009) C. Strassel et al.   HAEMATOLOGICA

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation

(2008) A. Eckly et al.   BLOOD

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY