Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice

Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: reversal by anti-tnfa treatment

(2019) Tiziano Balzano et al.   JOURNAL OF HEPATOLOGY

Direct comparison of the thioacetamide and azoxymethane models of Type A hepatic encephalopathy in mice

(2018) Stephanie Grant et al.   GENE EXPRESSION

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels

(2018) Starlee Lively et al.   Frontiers in Cellular Neuroscience

Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection

(2017) Dustin A. Cobb et al.   HEPATOLOGY

Animal models of neuroinflammation secondary to acute insults originated outside the brain

(2017) Mike Yoshio Hamasaki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cortical Synaptic Transmission and Plasticity in Acute Liver Failure Are Decreased by Presynaptic Events

(2017) Mariusz Popek et al.   MOLECULAR NEUROBIOLOGY

Neonatal Systemic Inflammation Induces Inflammatory Reactions and Brain Apoptosis in a Pathogen-Specific Manner

(2017) Mari Falck et al.   Neonatology

Neurological consequences of systemic inflammation in the premature neonate

(2017) Aparna Patra et al.   Neural Regeneration Research

Acute liver failure is associated with altered cerebral expression profiles of long non-coding RNAs

(2017) Vinícius R. Silva et al.   NEUROSCIENCE LETTERS

Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation

(2017) You Li et al.   STROKE

Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice

(2017) Matthew McMillin et al.   Frontiers in Cellular Neuroscience

Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure

(2016) Matthew McMillin et al.   AMERICAN JOURNAL OF PATHOLOGY

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage

(2016) Roslyn A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice

(2016) Matthew McMillin et al.   Journal of Neuroinflammation

Hyperammonaemia and associated factors in unprovoked convulsive seizures: A cross-sectional study

(2016) Kenichiro Sato et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

TGR5 signaling reduces neuroinflammation during hepatic encephalopathy

(2015) Matthew McMillin et al.   JOURNAL OF NEUROCHEMISTRY

TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5

(2015) Matthew A McMillin et al.   LABORATORY INVESTIGATION

Hepatic Encephalopathy in Chronic Liver Disease: 2014 Practice Guideline by the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases

(2014)   JOURNAL OF HEPATOLOGY

Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice

(2014) Matthew McMillin et al.   JOURNAL OF HEPATOLOGY

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

(2014) Matthew McMillin et al.   Journal of Neuroinflammation

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

(2014) Sung S. Choi et al.   PLoS One

Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain

(2013) Maj-Linda B Selenica et al.   Journal of Neuroinflammation

Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure

(2013) Anne Chastre et al.   LIVER INTERNATIONAL

Injury-Activated Transforming Growth Factor β Controls Mobilization of Mesenchymal Stem Cells for Tissue Remodeling

(2012) Mei Wan et al.   STEM CELLS

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

(2011) Gabriel Frampton et al.   GUT

Hepatic encephalopathy: A central neuroinflammatory disorder?

(2011) Roger F. Butterworth   HEPATOLOGY

Monocyte chemoattractant protein-1 is generated via TGF-β by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection

(2010) Hiroyuki Mutoh et al.   CANCER SCIENCE

Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy

(2010) Regina Rodrigo et al.   GASTROENTEROLOGY

TGF-β1 blockade of microglial chemotaxis toward Aβ aggregates involves SMAD signaling and down-regulation of CCL5

(2010) Wei-Chao Huang et al.   Journal of Neuroinflammation

Acute liver failure

(2010) William Bernal et al.   LANCET

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

(2008) Sharon DeMorrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY