Mutations in PB2 and HA enhanced pathogenicity of H4N6 avian influenza virus in mice

New Threats from H7N9 Influenza Virus: Spread and Evolution of High- and Low-Pathogenicity Variants with High Genomic Diversity in Wave Five

(2018) Chuansong Quan et al.   JOURNAL OF VIROLOGY

Development of a quadruple qRT-PCR assay for simultaneous identification of highly and low pathogenic H7N9 avian influenza viruses and characterization against oseltamivir resistance

(2018) Yang Yang et al.   BMC INFECTIOUS DISEASES

Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations

(2017) Xuxiao Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Rapid acquisition adaptive amino acid substitutions involved in the virulence enhancement of an H1N2 avian influenza virus in mice

(2017) Zhijun Yu et al.   VETERINARY MICROBIOLOGY

Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

(2017) Chunmao Zhang et al.   Frontiers in Microbiology

Adaptation of influenza A(H1N1)pdm09 virus in experimental mouse models

(2016) E.A. Prokopyeva et al.   INFECTION GENETICS AND EVOLUTION

Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity

(2016) Guanlong Xu et al.   JOURNAL OF VIROLOGY

Amino acid substitutions involved in the adaptation of a novel highly pathogenic H5N2 avian influenza virus in mice

(2016) Haibo Wu et al.   Virology Journal

Rapid emergence of a PB2-E627K substitution confers a virulent phenotype to an H9N2 avian influenza virus during adaption in mice

(2015) Xiaoyu Sang et al.   ARCHIVES OF VIROLOGY

Influenza Virus Adaptation PB2-627K Modulates Nucleocapsid Inhibition by the Pathogen Sensor RIG-I

(2015) Michaela Weber et al.   Cell Host & Microbe

Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China

(2015) Libin Liang et al.   JOURNAL OF VIROLOGY

Adaptive amino acid substitutions enhance the virulence of a reassortant H7N1 avian influenza virus isolated from wild waterfowl in mice

(2015) Zhijun Yu et al.   VIROLOGY

Genetic characterization of natural reassortant H4 subtype avian influenza viruses isolated from domestic ducks in Zhejiang province in China from 2013 to 2014

(2015) Haibo Wu et al.   VIRUS GENES

Adaptive mutations in PB2 gene contribute to the high virulence of a natural reassortant H5N2 avian influenza virus in mice

(2015) Qunhui Li et al.   VIRUS RESEARCH

Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts

(2015) Seiya Yamayoshi et al.   Scientific Reports

Analysis of Recombinant H7N9 Wild-Type and Mutant Viruses in Pigs Shows that the Q226L Mutation in HA Is Important for Transmission

(2014) Qinfang Liu et al.   JOURNAL OF VIROLOGY

Assessment of the Internal Genes of Influenza A (H7N9) Virus Contributing to High Pathogenicity in Mice

(2014) Yuhai Bi et al.   JOURNAL OF VIROLOGY

Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins

(2014) H. Yang et al.   JOURNAL OF VIROLOGY

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

(2014) HaiYing Chen et al.   LANCET

Characterization of Uncultivable Bat Influenza Virus Using a Replicative Synthetic Virus

(2014) Bin Zhou et al.   PLoS Pathogens

A Single Amino Acid in the Stalk Region of the H1N1pdm Influenza Virus HA Protein Affects Viral Fusion, Stability and Infectivity

(2014) Christopher R. Cotter et al.   PLoS Pathogens

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of an avian influenza virus of subtype H4N6 isolated from ducks in the northern China

(2013) Chuantian Xu et al.   VIRUS GENES

Human infection with avian influenza A H6N1 virus: an epidemiological analysis

(2013) Sung-Hsi Wei et al.   Lancet Respiratory Medicine

Seroepidemiological Evidence of Avian Influenza A Virus Transmission to Pigs in Southern China

(2012) S. Su et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Complete Genome Sequence of an Avian-Like H4N8 Swine Influenza Virus Discovered in Southern China

(2012) S. Su et al.   JOURNAL OF VIROLOGY

Complete Genome Sequence of a Novel H4N1 Influenza Virus Isolated from a Pig in Central China

(2012) Y. Hu et al.   JOURNAL OF VIROLOGY

Reversion of PB2-627E to -627K during Replication of an H5N1 Clade 2.2 Virus in Mammalian Hosts Depends on the Origin of the Nucleoprotein

(2011) J. Bogs et al.   JOURNAL OF VIROLOGY

Evidence of Infection with H4 and H11 Avian Influenza Viruses among Lebanese Chicken Growers

(2011) Ghazi Kayali et al.   PLoS One

Avian-origin H3N2 canine influenza A viruses in Southern China

(2010) Shoujun Li et al.   INFECTION GENETICS AND EVOLUTION

PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

(2010) B. Zhou et al.   JOURNAL OF VIROLOGY

Evidence of Previous Avian Influenza Infection among US Turkey Workers

(2009) G. Kayali et al.   Zoonoses and Public Health

Experimental Evolution of Human Influenza Virus H3 Hemagglutinin in the Mouse Lung Identifies Adaptive Regions in HA1 and HA2

(2008) L. Keleta et al.   JOURNAL OF VIROLOGY