Analysis of Recombinant H7N9 Wild-Type and Mutant Viruses in Pigs Shows that the Q226L Mutation in HA Is Important for Transmission

The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus

(2014) H. Zhang et al.   JOURNAL OF GENERAL VIROLOGY

Amino Acid Substitutions in Polymerase Basic Protein 2 Gene Contribute to the Pathogenicity of the Novel A/H7N9 Influenza Virus in Mammalian Hosts

(2014) C. K. P. Mok et al.   JOURNAL OF VIROLOGY

Human H7N9 Influenza A Viruses Replicate in Swine Respiratory Tissue Explants

(2013) J. C. Jones et al.   JOURNAL OF VIROLOGY

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses

(2013) Di Liu et al.   LANCET

The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities

(2013) Kelvin KW To et al.   LANCET INFECTIOUS DISEASES

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Limited airborne transmission of H7N9 influenza A virus between ferrets

(2013) Mathilde Richard et al.   NATURE

Receptor binding by an H7N9 influenza virus from humans

(2013) Xiaoli Xiong et al.   NATURE

Biological features of novel avian influenza A (H7N9) virus

(2013) Jianfang Zhou et al.   NATURE

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

(2013) P. R. Dormitzer et al.   Science Translational Medicine

Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus

(2012) C. Qiao et al.   JOURNAL OF GENERAL VIROLOGY

Cross-reactive and Vaccine-Induced Antibody to an Emerging Swine-Origin Variant of Influenza A Virus Subtype H3N2 (H3N2v)

(2012) Danuta M. Skowronski et al.   JOURNAL OF INFECTIOUS DISEASES

Key Molecular Factors in Hemagglutinin and PB2 Contribute to Efficient Transmission of the 2009 H1N1 Pandemic Influenza Virus

(2012) Ying Zhang et al.   JOURNAL OF VIROLOGY

Biochemical Impact of the Host Adaptation-associated PB2 E627K Mutation on the Temperature-dependent RNA Synthesis Kinetics of Influenza A Virus Polymerase Complex

(2011) Shilpa Aggarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reverse genetics plasmid for cloning unstable Influenza A virus gene segments

(2011) Bin Zhou et al.   JOURNAL OF VIROLOGICAL METHODS

Rapid detection of the pandemic 2009 H1N1 virus M gene by real-time and gel-based RT-PCR assays

(2010) Wenjun Ma et al.   Influenza and Other Respiratory Viruses

Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam

(2010) Q. M. Le et al.   JOURNAL OF GENERAL VIROLOGY

Viral reassortment and transmission after co-infection of pigs with classical H1N1 and triple-reassortant H3N2 swine influenza viruses

(2010) W. Ma et al.   JOURNAL OF GENERAL VIROLOGY

PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

(2010) K. A. Bussey et al.   JOURNAL OF VIROLOGY

PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

(2010) B. Zhou et al.   JOURNAL OF VIROLOGY

Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission

(2010) S. Herfst et al.   JOURNAL OF VIROLOGY

Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice

(2010) Huachen Zhu et al.   VIROLOGY

The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

(2010) B. W. Jagger et al.   mBio

Single-Reaction Genomic Amplification Accelerates Sequencing and Vaccine Production for Classical and Swine Origin Human Influenza A Viruses

(2009) B. Zhou et al.   JOURNAL OF VIROLOGY

Selection of H5N1 Influenza Virus PB2 during Replication in Humans

(2009) Q. M. Le et al.   JOURNAL OF VIROLOGY

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

(2009) Gavin J. D. Smith et al.   NATURE

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

The Role of Swine in the Generation of Novel Influenza Viruses

(2009) W. Ma et al.   Zoonoses and Public Health

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

PB2 Protein of a Highly Pathogenic Avian Influenza Virus Strain A/chicken/Yamaguchi/7/2004 (H5N1) Determines Its Replication Potential in Pigs

(2008) R. Manzoor et al.   JOURNAL OF VIROLOGY