Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations

Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity

(2016) Guanlong Xu et al.   JOURNAL OF VIROLOGY

Novel reassortant H10N7 avian influenza viruses isolated from chickens in Eastern China

(2015) Haibo Wu et al.   JOURNAL OF CLINICAL VIROLOGY

Emergence and Evolution of H10 Subtype Influenza Viruses in Poultry in China

(2015) Chi Ma et al.   JOURNAL OF VIROLOGY

Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus

(2015) Min Wang et al.   Nature Communications

Amino acids substitutions in the PB2 protein of H7N9 influenza A viruses are important for virulence in mammalian hosts

(2015) Seiya Yamayoshi et al.   Scientific Reports

First Evidence of H10N8 Avian Influenza Virus Infections among Feral Dogs in Live Poultry Markets in Guangdong Province, China

(2014) S. Su et al.   CLINICAL INFECTIOUS DISEASES

Avian influenza A(H10N7) virus involvement in mass mortality of harbour seals (Phoca vitulina) in Sweden, March through October 2014

(2014) S Zohari et al.   Eurosurveillance

Naturally Occurring Mutations in the PA Gene Are Key Contributors to Increased Virulence of Pandemic H1N1/09 Influenza Virus in Mice

(2014) Y. Sun et al.   JOURNAL OF VIROLOGY

A Combination of HA and PA Mutations Enhances Virulence in a Mouse-Adapted H6N6 Influenza A Virus

(2014) L. Tan et al.   JOURNAL OF VIROLOGY

Structure of Influenza Virus N7: the Last Piece of the Neuraminidase "Jigsaw" Puzzle

(2014) X. Sun et al.   JOURNAL OF VIROLOGY

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

(2014) HaiYing Chen et al.   LANCET

Receptor binding by H10 influenza viruses

(2014) Sebastien G. Vachieri et al.   NATURE

Central Nervous System Manifestations in Pediatric Patients With Influenza A H1N1 Infection During the 2009 Pandemic

(2014) Ashley N. Wilking et al.   PEDIATRIC NEUROLOGY

Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus

(2014) Juan Pu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel residues in avian influenza virus PB2 protein affect virulence in mammalian hosts

(2014) Shufang Fan et al.   Nature Communications

The Recent Establishment of North American H10 Lineage Influenza Viruses in Australian Wild Waterfowl and the Evolution of Australian Avian Influenza Viruses

(2013) D. Vijaykrishna et al.   JOURNAL OF VIROLOGY

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Asparagine Substitution at PB2 Residue 701 Enhances the Replication, Pathogenicity, and Transmission of the 2009 Pandemic H1N1 Influenza A Virus

(2013) Bin Zhou et al.   PLoS One

H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

(2013) Y. Zhang et al.   SCIENCE

Complete Genome Sequence of an H10N5 Avian Influenza Virus Isolated from Pigs in Central China

(2012) N. Wang et al.   JOURNAL OF VIROLOGY

Amino Acid 316 of Hemagglutinin and the Neuraminidase Stalk Length Influence Virulence of H9N2 Influenza Virus in Chickens and Mice

(2012) Y. Sun et al.   JOURNAL OF VIROLOGY

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Neurologic complications of influenza A(H1N1)pdm09: Surveillance in 6 pediatric hospitals

(2012) G. Khandaker et al.   NEUROLOGY

Mouse-Adapted H9N2 Influenza A Virus PB2 Protein M147L and E627K Mutations Are Critical for High Virulence

(2012) Jingjing Wang et al.   PLoS One

High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses

(2011) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PA Protein Directly Contributes to the Virulence of H5N1 Avian Influenza Viruses in Domestic Ducks

(2010) J. Song et al.   JOURNAL OF VIROLOGY

PB2 and Hemagglutinin Mutations Are Major Determinants of Host Range and Virulence in Mouse-Adapted Influenza A Virus

(2010) Jihui Ping et al.   JOURNAL OF VIROLOGY

Adaptation of Pandemic H1N1 Influenza Viruses in Mice

(2010) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

PB2 Residue 158 Is a Pathogenic Determinant of Pandemic H1N1 and H5 Influenza A Viruses in Mice

(2010) B. Zhou et al.   JOURNAL OF VIROLOGY

Modifications to the Hemagglutinin Cleavage Site Control the Virulence of a Neurotropic H1N1 Influenza Virus

(2010) X. Sun et al.   JOURNAL OF VIROLOGY

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of Previous Avian Influenza Infection among US Turkey Workers

(2009) G. Kayali et al.   Zoonoses and Public Health

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Experimental Evolution of Human Influenza Virus H3 Hemagglutinin in the Mouse Lung Identifies Adaptive Regions in HA1 and HA2

(2008) L. Keleta et al.   JOURNAL OF VIROLOGY

Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: insights into viral virulence, tissue tropism and host pathogenesis

(2008) T NARASARAJU et al.   MICROBES AND INFECTION

Evidence of Expanded Host Range and Mammalian-Associated Genetic Changes in a Duck H9N2 Influenza Virus Following Adaptation in Quail and Chickens

(2008) Md Jaber Hossain et al.   PLoS One

Changes in H5N1 influenza virus hemagglutinin receptor binding domain affect systemic spread

(2008) H.-L. Yen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA