p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer

Expression and role of autophagy-associated p62 (SQSTM1) in multidrug resistant ovarian cancer

(2018) Jinglu Wang et al.   GYNECOLOGIC ONCOLOGY

Indomethacin Disrupts Autophagic Flux by Inducing Lysosomal Dysfunction in Gastric Cancer Cells and Increases Their Sensitivity to Cytotoxic Drugs

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p62 in Cancer: Signaling Adaptor Beyond Autophagy

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Studying platinum sensitivity and resistance in high-grade serous ovarian cancer: Different models for different questions

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Autophagy core machinery: overcoming spatial barriers in neurons

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High Expression of p62 Protein Is Associated with Poor Prognosis and Aggressive Phenotypes in Endometrial Cancer

(2015) Reiko Iwadate et al.   AMERICAN JOURNAL OF PATHOLOGY

New mechanisms for old drugs: Insights into DNA-unrelated effects of platinum compounds and drug resistance determinants

(2015) Laura Gatti et al.   DRUG RESISTANCE UPDATES

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

p62/SQSTM1 is involved in caspase-8 associated cell death induced by proteasome inhibitor MG132 in U87MG cells

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Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures

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Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

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(2014) L Galluzzi et al.   Cell Death & Disease

Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling

(2013) Junyan Shi et al.   Autophagy

Interaction Domains of p62: A Bridge Between p62 and Selective Autophagy

(2013) Xiaolong Lin et al.   DNA AND CELL BIOLOGY

p62/Sequestosome-1 Up-regulation Promotes ABT-263-induced Caspase-8 Aggregation/Activation on the Autophagosome

(2013) Shengbing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8

(2013) Y Li et al.   Cell Death & Disease

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

(2013) Y-B Zhang et al.   Cell Death & Disease

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells

(2012) Jing Zhou et al.   Autophagy

Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

(2012) Megan M. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins

(2011) Huimei Yu et al.   EUROPEAN JOURNAL OF CANCER

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Caspase-8 as a therapeutic target in cancer

(2010) Dwayne G. Stupack   CANCER LETTERS

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling

(2009) Zhaoyu Jin et al.   CELL

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Alternative Fas-mediated cell death pathway is dependent on the different cleavage patterns of procaspase-8

(2009) Yufeng Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY