A unique role for clathrin light chain A in cell spreading and migration

Cargo regulates clathrin-coated pit invagination via clathrin light chain phosphorylation

(2018) Hannes Maib et al.   JOURNAL OF CELL BIOLOGY

Tubular clathrin/AP-2 lattices pinch collagen fibers to support 3D cell migration

(2017) Nadia Elkhatib et al.   SCIENCE

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors

(2017) Daniela Leyton-Puig et al.   Nature Communications

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

(2017) Baoyu Chen et al.   eLife

Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge

(2016) Guillermo Ramírez-Santiago et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly

(2016) Guilherme P. F. Nader et al.   NATURE CELL BIOLOGY

Clathrin light chains’ role in selective endocytosis influences antibody isotype switching

(2016) Shuang Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

(2016) Marina Theodosiou et al.   eLife

Endocytic membrane trafficking and neurodegenerative disease

(2015) Andrea M. A. Schreij et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Integrin endosomal signalling suppresses anoikis

(2015) Jonna Alanko et al.   NATURE CELL BIOLOGY

DRE-1/FBXO11-Dependent Degradation of BLMP-1/BLIMP-1 Governs C. elegans Developmental Timing and Maturation

(2014) Moritz Horn et al.   DEVELOPMENTAL CELL

LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation

(2014) A. M. Schreij et al.   EMBO REPORTS

Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh

(2014) Aurélien Rizk et al.   Nature Protocols

Unconventional Functions for Clathrin, ESCRTs, and Other Endocytic Regulators in the Cytoskeleton, Cell Cycle, Nucleus, and Beyond: Links to Human Disease

(2014) F. M. Brodsky et al.   Cold Spring Harbor Perspectives in Biology

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration

(2014) Sophia R. Majeed et al.   Nature Communications

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits

(2014) Mirko Messa et al.   eLife

Dynamic Regulation of the Structure and Functions of Integrin Adhesions

(2013) Haguy Wolfenson et al.   DEVELOPMENTAL CELL

Tumor Cell Migration and Invasion Are Enhanced by Depletion of Rap1 GTPase-activating Protein (Rap1GAP)

(2013) Oxana M. Tsygankova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The non-canonical roles of clathrin and actin in pathogen internalization, egress and spread

(2013) Ashley C. Humphries et al.   NATURE REVIEWS MICROBIOLOGY

Cargo Recognition in Clathrin-Mediated Endocytosis

(2013) L. M. Traub et al.   Cold Spring Harbor Perspectives in Biology

Diversity of Clathrin Function: New Tricks for an Old Protein

(2012) Frances M. Brodsky   Annual Review of Cell and Developmental Biology

Endocytosis of G Protein-Coupled Receptors Is Regulated by Clathrin Light Chain Phosphorylation

(2012) Filipe Ferreira et al.   CURRENT BIOLOGY

Focal adhesion size uniquely predicts cell migration

(2012) Dong-Hwee Kim et al.   FASEB JOURNAL

The role of clathrin in mitotic spindle organisation

(2012) S. J. Royle   JOURNAL OF CELL SCIENCE

Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis

(2012) M. Skruzny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arf6 Regulation of Gyrating-Clathrin

(2012) Yi Luo et al.   TRAFFIC

Distinct Recycling of Active and Inactive β1 Integrins

(2012) Antti Arjonen et al.   TRAFFIC

Signaling Network Triggers and Membrane Physical Properties Control the Actin Cytoskeleton-Driven Isotropic Phase of Cell Spreading

(2011) Padmini Rangamani et al.   BIOPHYSICAL JOURNAL

Structural Organization of the Actin Cytoskeleton at Sites of Clathrin-Mediated Endocytosis

(2011) Agnieszka Collins et al.   CURRENT BIOLOGY

GGA3 Functions as a Switch to Promote Met Receptor Recycling, Essential for Sustained ERK and Cell Migration

(2011) Christine Anna Parachoniak et al.   DEVELOPMENTAL CELL

Interplay between N-WASP and CK2 optimizes clathrin-mediated endocytosis of EGFR

(2011) M. Galovic et al.   JOURNAL OF CELL SCIENCE

Clathrin is required for Scar/Wave-mediated lamellipodium formation

(2011) J. J. Gautier et al.   JOURNAL OF CELL SCIENCE

Endosomal clathrin drives actin accumulation at the immunological synapse

(2011) C. Calabia-Linares et al.   JOURNAL OF CELL SCIENCE

Divalent cations regulate the folding and activation status of integrins during their intracellular trafficking

(2011) S. Tiwari et al.   JOURNAL OF CELL SCIENCE

Integrins in Cell Migration

(2011) A. Huttenlocher et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms Controlling Cell Size and Shape during Isotropic Cell Spreading

(2010) Yuguang Xiong et al.   BIOPHYSICAL JOURNAL

Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell Adhesion

(2010) O. M. Tsygankova et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of tyrosine phosphatase-dependent inhibition promotes activation of tyrosine kinase c-Src in detached pancreatic cells

(2010) Sarah F. Connelly et al.   MOLECULAR CARCINOGENESIS

Cell spreading as a hydrodynamic process

(2010) M. A. Fardin et al.   Soft Matter

The Membrane-Associated Protein, Supervillin, Accelerates F-Actin-Dependent Rapid Integrin Recycling and Cell Motility

(2010) Zhiyou Fang et al.   TRAFFIC

Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

(2009) Wei-Ting Chao et al.   FEBS LETTERS

Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells

(2009) Ellen J. Ezratty et al.   JOURNAL OF CELL BIOLOGY

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Anti-integrin monoclonal antibodies

(2009) A. Byron et al.   JOURNAL OF CELL SCIENCE

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Activation of the WAVE Complex by Coincident Signals Controls Actin Assembly

(2009) Andres M. Lebensohn et al.   MOLECULAR CELL

Endocytic Trafficking of Rac Is Required for the Spatial Restriction of Signaling in Cell Migration

(2008) Andrea Palamidessi et al.   CELL

Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

(2008) Colin K. Choi et al.   NATURE CELL BIOLOGY

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

(2008) Xian Zhang et al.   NATURE CELL BIOLOGY

Gyrating Clathrin: Highly Dynamic Clathrin Structures Involved in Rapid Receptor Recycling

(2008) Yanqiu Zhao et al.   TRAFFIC