Tumor Cell Migration and Invasion Are Enhanced by Depletion of Rap1 GTPase-activating Protein (Rap1GAP)

Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion

(2011) Lisa A. Vuchak et al.   Cell Adhesion & Migration

Laminin regulates mouse embryonic stem cell migration: involvement of Epac1/Rap1 and Rac1/cdc42

(2010) Han Na Suh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Downregulation of Rap1GAP through Epigenetic Silencing and Loss of Heterozygosity Promotes Invasion and Progression of Thyroid Tumors

(2010) H. Zuo et al.   CANCER RESEARCH

Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the Lungs

(2010) Spencer A. Freeman et al.   CANCER RESEARCH

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

(2010) Victoria Sanz-Moreno et al.   CURRENT OPINION IN CELL BIOLOGY

Downregulation of Rap1GAP in Human Tumor Cells Alters Cell/Matrix and Cell/Cell Adhesion

(2010) O. M. Tsygankova et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of Motility in Metastasizing Cells

(2010) Mahmut Yilmaz et al.   MOLECULAR CANCER RESEARCH

Down-regulation of Rap1GAP via Promoter Hypermethylation Promotes Melanoma Cell Proliferation, Survival, and Migration

(2009) H. Zheng et al.   CANCER RESEARCH

Activation of Rap1 Promotes Prostate Cancer Metastasis

(2009) C. L. Bailey et al.   CANCER RESEARCH

Control of cell adhesion dynamics by Rap1 signaling

(2009) Benjamin Boettner et al.   CURRENT OPINION IN CELL BIOLOGY

Mutation Analysis of RAP1 Gene in Papillary Thyroid Carcinomas

(2009) Michiko MATSUSE et al.   ENDOCRINE JOURNAL

The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas

(2009) K B L Lin et al.   ONCOGENE

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Highlighting the role of Ras and Rap during Dictyostelium chemotaxis

(2008) Arjan Kortholt et al.   CELLULAR SIGNALLING

Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells

(2008) Motonori Takahashi et al.   GENES TO CELLS

E-cadherin dis-engagement activates the Rap1 GTPase

(2008) Sirisha Asuri et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Loss of Rap1GAP in Papillary Thyroid Cancer

(2008) Anoma Nellore et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM