The complement receptor C5aR2 promotes protein kinase R expression and contributes to NLRP3 inflammasome activation and HMGB1 release from macrophages
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The complement receptor C5aR2 promotes protein kinase R expression and contributes to NLRP3 inflammasome activation and HMGB1 release from macrophages
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 294, Issue 21, Pages 8384-8394
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2019-04-11
DOI
10.1074/jbc.ra118.006508
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of complement C5a and histones in septic cardiomyopathy
- (2018) Fatemeh Fattahi et al. MOLECULAR IMMUNOLOGY
- Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity
- (2018) Sujun Li et al. MOLECULAR MEDICINE
- C5a anaphylatoxin and its role in critical illness-induced organ dysfunction
- (2018) Alexander JT Wood et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis
- (2017) Hanif J. Khameneh et al. Frontiers in Pharmacology
- NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy
- (2017) Beibei Luo et al. Frontiers in Physiology
- The Controversial C5a Receptor C5aR2: Its Role in Health and Disease
- (2017) Ting Zhang et al. Journal of Immunology Research
- Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis
- (2016) Miriam Kalbitz et al. FASEB JOURNAL
- Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes
- (2016) Mikel D. Haggadone et al. MEDIATORS OF INFLAMMATION
- T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
- (2016) G. Arbore et al. SCIENCE
- PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
- (2016) Min Xie et al. Nature Communications
- p58IPK suppresses NLRP3 inflammasome activation and IL-1β production via inhibition of PKR in macrophages
- (2016) Evgenii Boriushkin et al. Scientific Reports
- Mechanism of NLRP3 inflammasome activation
- (2014) Fayyaz S. Sutterwala et al. Annals of the New York Academy of Sciences
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- Complement C5a potentiates uric acid crystal-induced IL-1β production
- (2014) Ling-Ling An et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression
- (2014) Gui-lian Xu et al. HEPATOLOGY
- C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment
- (2014) Daniel E Croker et al. IMMUNOLOGY AND CELL BIOLOGY
- Critical Role for the NLRP3 Inflammasome during Acute Lung Injury
- (2014) J. J. Grailer et al. JOURNAL OF IMMUNOLOGY
- The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation
- (2013) Markus Bosmann et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
- (2013) Erik C Hett et al. Nature Chemical Biology
- Inflammasomes and Their Roles in Health and Disease
- (2012) Mohamed Lamkanfi et al. Annual Review of Cell and Developmental Biology
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
- (2012) Haitao Wen et al. NATURE IMMUNOLOGY
- The inflammasome: an integrated view
- (2011) Olaf Gross et al. IMMUNOLOGICAL REVIEWS
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia
- (2010) M. Lamkanfi et al. JOURNAL OF IMMUNOLOGY
- NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways
- (2009) S. B. Willingham et al. JOURNAL OF IMMUNOLOGY
- Complexity of complement activation in sepsis
- (2008) Maciej M. Markiewski et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Functional roles for C5a receptors in sepsis
- (2008) Daniel Rittirsch et al. NATURE MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now