An MEDT study of the mechanism and selectivities of the [3+2] cycloaddition reaction of tomentosin with benzonitrile oxide

New development in the enantioselective synthesis of spiro compounds

(2018) Aishun Ding et al.   CHEMICAL SOCIETY REVIEWS

A Molecular Electron Density Theory Study of the Reactivity and Selectivities in [3 + 2] Cycloaddition Reactions of C,N-Dialkyl Nitrones with Ethylene Derivatives

(2018) Luis R. Domingo et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereoselective synthesis of novel spiro indanone fused pyrano[3,2-c]chromene derivatives following hetero-Diels–Alder reaction and in vitro anticancer studies

(2018) Pravati Panda et al.   RSC Advances

Unravelling the Mysteries of [3+2] Cycloaddition Reactions

(2018) Mar Ríos-Gutiérez et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Domino aza/oxa-hetero-Diels–Alder reaction for construction of novel spiro[pyrido[3′,2′:5,6]pyrano[2,3-d]pyrimidine-7,5′-pyrimidine]

(2018) Wen-Juan Yang et al.   Organic Chemistry Frontiers

Synthesis of Spiro[oxindole-3,2′-pyrrolidine] Derivatives from Benzynes and Azomethine Ylides through 1,3-Dipolar Cycloaddition Reactions

(2018) Heesun Ryu et al.   JOURNAL OF ORGANIC CHEMISTRY

Understanding the reactivity and regioselectivity of [3 + 2] cycloaddition reactions between substituted nitrile oxides and methyl acrylate. A molecular electron density theory study

(2017) Ibrahim Mbouombouo Ndassa et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

How does the global electron density transfer diminish activation energies in polar cycloaddition reactions? A Molecular Electron Density Theory study

(2017) Luis R. Domingo et al.   TETRAHEDRON

Synthesis of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of tomentosin

(2017) Mohamed Zaki et al.   RSC Advances

Effects of Spiro-bisheterocycles on Proliferation and Apoptosis in Human Breast Cancer Cell Lines

(2016) LAMIA HAMDAN RAMDANI et al.   ANTICANCER RESEARCH

Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity

(2016) Luis Domingo et al.   MOLECULES

Molecular Electron Density Theory: A Modern View of Reactivity in Organic Chemistry

(2016) Luis Domingo   MOLECULES

Synthesis and investigation of novel spiro-isoxazolines as anti-cancer agents

(2015) Prasanta Das et al.   TETRAHEDRON LETTERS

The use of spirocyclic scaffolds in drug discovery

(2014) Yajun Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A DFT analysis of the participation of zwitterionic TACs in polar [3+2] cycloaddition reactions

(2014) Luis R. Domingo et al.   TETRAHEDRON

A new C–C bond formation model based on the quantum chemical topology of electron density

(2014) Luis R. Domingo   RSC Advances

Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin

(2013) Jabeena Khazir et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Understanding the local reactivity in polar organic reactions through electrophilic and nucleophilic Parr functions

(2012) Luis R. Domingo et al.   RSC Advances

Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents

(2011) Doma Mahendhar Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

NCIPLOT: A Program for Plotting Noncovalent Interaction Regions

(2011) Julia Contreras-García et al.   Journal of Chemical Theory and Computation

Understanding the kinetic solvent effects on the 1,3-dipolar cycloaddition of benzonitrile N-oxide: a DFT study

(2011) W. Benchouk et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Spiro Isoxazolines via Nitrile Oxide 1,3-Dipolar Cycloaddition Reactions

(2010) G. Paul Savage   CURRENT ORGANIC CHEMISTRY

Revealing Noncovalent Interactions

(2010) Erin R. Johnson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding the Participation of Quadricyclane as Nucleophile in Polar [2σ + 2σ + 2π] Cycloadditions toward Electrophilic π Molecules

(2008) Luis R. Domingo et al.   JOURNAL OF ORGANIC CHEMISTRY

Understanding the Reactivity of Captodative Ethylenes in Polar Cycloaddition Reactions. A Theoretical Study†

(2008) Luis R. Domingo et al.   JOURNAL OF ORGANIC CHEMISTRY