Bridging the Gap between Alzheimer’s Disease and Alzheimer’s-like Diseases in Animals

Alzheimer's disease in humans and other animals: A consequence of postreproductive life span and longevity rather than aging

(2018) Danièlle Gunn-Moore et al.   Alzheimers & Dementia

MicroRNA Expression Levels Are Altered in the Cerebrospinal Fluid of Patients with Young-Onset Alzheimer’s Disease

(2018) Paul M. McKeever et al.   MOLECULAR NEUROBIOLOGY

Early Alzheimer-type lesions in cognitively normal subjects

(2018) Stergios Tsartsalis et al.   NEUROBIOLOGY OF AGING

Peptides isolated from animal venom as a platform for new therapeutics for the treatment of Alzheimer's disease

(2018) L.C. Camargo et al.   NEUROPEPTIDES

The Therapeutic Potential of Metformin in Neurodegenerative Diseases

(2018) Carola Rotermund et al.   Frontiers in Endocrinology

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease

(2018) Ulf Neumann et al.   EMBO Molecular Medicine

Expression of p75NTR, a Marker for Basal Forebrain Cholinergic Neurons, in Young and Aged Dogs with or without Cognitive Dysfunction Syndrome

(2018) Daniel Insua et al.   JOURNAL OF ALZHEIMERS DISEASE

Biomarkers for Preclinical Alzheimer's Disease

(2018) Chen-Chen Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

Exosomes and microRNAs: New potential therapeutic candidates in Alzheimer disease therapy

(2018) Elmira Iranifar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Longevity and sexual maturity vary across species with number of cortical neurons, and humans are no exception

(2018) Suzana Herculano-Houzel   JOURNAL OF COMPARATIVE NEUROLOGY

Acetylcholinesterase inhibitors for treating dementia symptoms - a safety evaluation

(2017) Dana Mohammad et al.   Expert Opinion On Drug Safety

Therapeutic effects of drug switching between acetylcholinesterase inhibitors in patients with Alzheimer's disease

(2017) Yasuyuki Ohta et al.   Geriatrics & Gerontology International

Insights into the protective role of immunity in neurodegenerative disease

(2017) Cristoforo Comi et al.   Neural Regeneration Research

Structural MRI and Amyloid PET Imaging for Prediction of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Meta-Analysis

(2017) Eun Hyun Seo et al.   Psychiatry Investigation

A Rare Success against Alzheimer's

(2017) Miia Kivipelto et al.   SCIENTIFIC AMERICAN

Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology

(2017) Mohammad Javad Hajipour et al.   TRENDS IN BIOTECHNOLOGY

Association between blood pressure and Alzheimer disease measured up to 27 years prior to diagnosis: the HUNT Study

(2017) Jessica Mira Gabin et al.   Alzheimers Research & Therapy

Amyloid-β Peptide and Oligomers in the Brain and Cerebrospinal Fluid of Aged Canines

(2017) Elizabeth Head et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

Reprint of: Microglial toll-like receptors and Alzheimer’s disease

(2016) Fan Su et al.   BRAIN BEHAVIOR AND IMMUNITY

Does the Interplay Between Aging and Neuroinflammation Modulate Alzheimer’s Disease Clinical Phenotypes? A Clinico-Pathological Perspective

(2016) Ricardo Taipa et al.   JOURNAL OF ALZHEIMERS DISEASE

Characterization of Amyloid-β Deposits in Bovine Brains

(2016) Elena Vallino Costassa et al.   JOURNAL OF ALZHEIMERS DISEASE

Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer’s Disease: A Translational Study of Neuropathological and Inflammatory Markers

(2016) Trine Schütt et al.   JOURNAL OF ALZHEIMERS DISEASE

Growth Arrest Specific 6 Concentration is Increased in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease

(2016) Pier Paolo Sainaghi et al.   JOURNAL OF ALZHEIMERS DISEASE

Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease

(2016) Ahsan Habib et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Natural or pathologic? Discrepancies in the study of behavioral and cognitive signs in aging family dogs

(2016) Dóra Szabó et al.   Journal of Veterinary Behavior-Clinical Applications and Research

Natural or pathologic? Discrepancies in the study of behavioral and cognitive signs in aging family dogs

(2016) Dóra Szabó et al.   Journal of Veterinary Behavior-Clinical Applications and Research

Early Alzheimer's disease–type pathology in the frontal cortex of wild mountain gorillas ( Gorilla beringei beringei )

(2016) Sylvia E. Perez et al.   NEUROBIOLOGY OF AGING

Pathology of the Aging Brain in Domestic and Laboratory Animals, and Animal Models of Human Neurodegenerative Diseases

(2016) S. A. Youssef et al.   VETERINARY PATHOLOGY

In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

(2016) Farron L. McIntee et al.   Frontiers in Aging Neuroscience

The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury

(2016) Stephanie Plummer et al.   Aging and Disease

miRNA expression profiles in cerebrospinal fluid and blood of patients with Alzheimer’s disease and other types of dementia – an exploratory study

(2016) Sofie Sølvsten Sørensen et al.   Translational Neurodegeneration

Aging on a different scale – chronological versus pathology-related aging

(2016) Joost P.M. Melis et al.   Aging-US

Invited review: Neuropathology of tauopathies: principles and practice

(2015) G. G. Kovacs   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

β-amyloid, microglia, and the inflammasome in Alzheimer’s disease

(2015) Maike Gold et al.   Seminars in Immunopathology

Animal-assisted therapy at Mayo Clinic: The time is now

(2015) Edward T. Creagan et al.   Complementary Therapies in Clinical Practice

The domestic cat as a natural animal model of Alzheimer’s disease

(2015) James K. Chambers et al.   Acta Neuropathologica Communications

Microglial Aβ Receptors in Alzheimer’s Disease

(2014) Yang Yu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Amyloid-Beta: A Crucial Factor in Alzheimer's Disease

(2014) Saeed Sadigh-Eteghad et al.   MEDICAL PRINCIPLES AND PRACTICE

Amyloid-� Immunotherapy Reduces Amyloid Plaques and Astroglial Reaction in Aged Domestic Dogs

(2014) Maria Neus Bosch et al.   Neurodegenerative Diseases

Scorpion Venom Heat-Resistant Peptide (SVHRP) Enhances Neurogenesis and Neurite Outgrowth of Immature Neurons in Adult Mice by Up-Regulating Brain-Derived Neurotrophic Factor (BDNF)

(2014) Tao Wang et al.   PLoS One

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

A canine model of human aging and Alzheimer's disease

(2013) Elizabeth Head   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circulating MicroRNAs: A Novel Class of Potential Biomarkers for Diagnosing and Prognosing Central Nervous System Diseases

(2013) Xue-Feng Jin et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

(2013) Dan Frenkel et al.   Nature Communications

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

The Role of Astrocytes in the Regulation of Synaptic Plasticity and Memory Formation

(2013) Yusuke Ota et al.   NEURAL PLASTICITY

Metal dyshomeostasis and oxidative stress in Alzheimer’s disease

(2012) Mark A. Greenough et al.   NEUROCHEMISTRY INTERNATIONAL

TLR2 Is a Primary Receptor for Alzheimer's Amyloid   Peptide To Trigger Neuroinflammatory Activation

(2011) S. Liu et al.   JOURNAL OF IMMUNOLOGY

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal  -Catenin Pathway Function in an Alzheimer's Disease Model

(2011) M. Kitazawa et al.   JOURNAL OF IMMUNOLOGY

Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons

(2011) M. Ndung'u et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

The canine cognitive dysfunction rating scale (CCDR): A data-driven and ecologically relevant assessment tool

(2010) Hannah E. Salvin et al.   VETERINARY JOURNAL

Parenchymal and Vascular Lesions in Ageing Equine Brains: Histological and Immunohistochemical Studies

(2009) M.T. Capucchio et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Cytokines and CNS Development

(2009) Benjamin E. Deverman et al.   NEURON

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

(2008) Dick Terwel et al.   AMERICAN JOURNAL OF PATHOLOGY

Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease

(2008) Henrik Zetterberg et al.   ARCHIVES OF NEUROLOGY

Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-β precursor protein (APP) levels in the aged dog

(2008) Christa M. Studzinski et al.   BRAIN RESEARCH

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study

(2008) P Lewczuk et al.   MOLECULAR PSYCHIATRY

Dogs with canine counterpart of Alzheimer's disease lose noradrenergic neurons

(2008) Daniel Insua et al.   NEUROBIOLOGY OF AGING

Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3

(2007) Seong-Ho Koh et al.   BRAIN RESEARCH

Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

(2007) Maryse Letiembre et al.   NEUROBIOLOGY OF AGING