Citrate-Induced p85α–PTEN Complex Formation Causes G2/M Phase Arrest in Human Pharyngeal Squamous Carcinoma Cell Lines

Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway

(2017) Jian-Guo Ren et al.   Scientific Reports

Dichloroacetate restores drug sensitivity in paclitaxel-resistant cells by inducing citric acid accumulation

(2015) Xiang Zhou et al.   Molecular Cancer

Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium

(2015) Lydia WT Cheung et al.   eLife

Suppression of PI3K/Akt signaling by synthetic bichalcone analog TSWU-CD4 induces ER stress- and Bax/Bak-mediated apoptosis of cancer cells

(2014) Meng-Liang Lin et al.   APOPTOSIS

Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin

(2014) Mohamed S. Taha et al.   PLoS One

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Inhibition of Mcl-1 expression by citrate enhances the effect of Bcl-xL inhibitors on human ovarian carcinoma cells

(2013) Hubert Lincet et al.   Journal of Ovarian Research

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

ATP-Citrate Lyase: A Key Player in Cancer Metabolism

(2012) N. Zaidi et al.   CANCER RESEARCH

Understanding the central role of citrate in the metabolism of cancer cells

(2011) Philippe Icard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells

(2011) Y. Zhou et al.   CANCER RESEARCH

Reversible High Affinity Inhibition of Phosphofructokinase-1 by Acyl-CoA

(2011) Christopher M. Jenkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WWP2 is an E3 ubiquitin ligase for PTEN

(2011) Subbareddy Maddika et al.   NATURE CELL BIOLOGY

Effects of citric acid on cultured human osteoblastic cells

(2010) Lizandra Ferrari Guimarães et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase

(2010) R. B. Chagpar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation keeps PTEN phosphatase closed for business

(2009) A. H. Ross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA