Suppression of PI3K/Akt signaling by synthetic bichalcone analog TSWU-CD4 induces ER stress- and Bax/Bak-mediated apoptosis of cancer cells

Endoplasmic reticulum stress inhibits cell cycle progression via induction of p27 in melanoma cells

(2012) Chuanchun Han et al.   CELLULAR SIGNALLING

Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis

(2012) Colins O. Eno et al.   MOLECULAR BIOLOGY OF THE CELL

Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells

(2012) Meng-Liang Lin et al.   MOLECULAR CARCINOGENESIS

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Preparation of a Series of Novel Bichalcones Linked with a 1,4-Dimethylenepiperazine Moiety and Examination of Their Cytotoxicity

(2011) Mopuru Vijaya Bhaskar Reddy et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner

(2011) Hong Wa Yung et al.   PLoS One

Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control

(2011) M. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt Determines Cell Fate Through Inhibition of the PERK-eIF2  Phosphorylation Pathway

(2011) Z. Mounir et al.   Science Signaling

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response

(2010) Jonathon N Winnay et al.   NATURE MEDICINE

Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

(2009) Meng-Liang Lin et al.   CANCER LETTERS

Inhibition of the ER Ca 2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis

(2009) Katja Janssen et al.   JOURNAL OF CELL SCIENCE

FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival

(2008) Cécilie Dufour et al.   BONE

Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

(2008) Lieven P Billen et al.   PLOS BIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY