Mitochondrial-Derived Vesicles as Candidate Biomarkers in Parkinson’s Disease: Rationale, Design and Methods of the EXosomes in PArkiNson Disease (EXPAND) Study

Modulation of RAB7A Protein Expression Determines Resistance to Cisplatin through Late Endocytic Pathway Impairment and Extracellular Vesicular Secretion

(2019) Flora Guerra et al.   Cancers

Mitochondrial Dysfunction and Aging: Insights from the Analysis of Extracellular Vesicles

(2019) Anna Picca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleic acid aptamers for neurodegenerative diseases

(2018) Alix Bouvier-Müller et al.   BIOCHIMIE

The genetic architecture of mitochondrial dysfunction in Parkinson’s disease

(2018) S. B. Larsen et al.   CELL AND TISSUE RESEARCH

Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders

(2018) Anna Picca et al.   REJUVENATION RESEARCH

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease

(2018) Sandra Franco-Iborra et al.   Frontiers in Neuroscience

Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease

(2018) Mengke Qu et al.   JOURNAL OF CONTROLLED RELEASE

Mitochondrial quality control mechanisms as molecular targets in cardiac ageing

(2018) Anna Picca et al.   Nature Reviews Cardiology

A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers

(2018) Andrés Norambuena et al.   EMBO JOURNAL

HmtVar: a new resource for human mitochondrial variations and pathogenicity data

(2018) Roberto Preste et al.   NUCLEIC ACIDS RESEARCH

Molecular mechanisms of biogenesis of apoptotic exosome-like vesicles and their roles as damage-associated molecular patterns

(2018) Soo Jeong Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Distinct Pattern of Circulating Amino Acids Characterizes Older Persons with Physical Frailty and Sarcopenia: Results from the BIOSPHERE Study

(2018) Riccardo Calvani et al.   Nutrients

The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease

(2018) Alice J. White et al.   Frontiers in Neurology

Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization

(2017) Giulia Girolimetti et al.   HUMAN MOLECULAR GENETICS

Fueling Inflamm-Aging through Mitochondrial Dysfunction: Mechanisms and Molecular Targets

(2017) Anna Picca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Engineered exosomes emerging from muscle cells break immune tolerance to HER2 in transgenic mice and induce antigen-specific CTLs upon challenge by human dendritic cells

(2017) Simona Anticoli et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

T cells from patients with Parkinson’s disease recognize α-synuclein peptides

(2017) David Sulzer et al.   NATURE

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

(2017) Pasquale Sansone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does eating less make you live longer and better? An update on calorie restriction

(2017) Anna Picca et al.   Clinical Interventions in Aging

Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

(2016) Diana Matheoud et al.   CELL

Mitochondrial DNA homeostasis is essential for nigrostriatal integrity

(2016) Charalampos Tzoulis et al.   MITOCHONDRION

Exosomes as a potential novel therapeutic tools against neurodegenerative diseases

(2016) Akvilė Jarmalavičiūtė et al.   PHARMACOLOGICAL RESEARCH

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease

(2016) Christian Dölle et al.   Nature Communications

Si- and C-Functional Organosilicon Building Blocks for Synthesis Based on 4-Silacyclohexan-1-ones Containing the Silicon Protecting Groups MOP (4-Methoxyphenyl), DMOP (2,6-Dimethoxyphenyl), or TMOP (2,4,6-Trimethoxyphenyl)

(2015) Marcel Geyer et al.   JOURNAL OF ORGANIC CHEMISTRY

Proteolytic enzymes involved in MHC class I antigen processing: A guerrilla army that partners with the proteasome

(2015) Silvia Lázaro et al.   MOLECULAR IMMUNOLOGY

Mitochondrial DNA stress primes the antiviral innate immune response

(2015) A. Phillip West et al.   NATURE

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Oxidative stress and Parkinson’s disease

(2015) Javier Blesa et al.   Frontiers in Neuroanatomy

Extracellular vesicles as emerging intercellular communicasomes

(2014) Yae Jin Yoon et al.   BMB Reports

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

(2014) Gian-Luca McLelland et al.   EMBO JOURNAL

Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1

(2014) Taku Amo et al.   NEUROSCIENCE LETTERS

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

(2014) Carolina Cebrián et al.   Nature Communications

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

MHCII Is Required for  -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

(2013) A. S. Harms et al.   JOURNAL OF NEUROSCIENCE

Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging

(2013) Jenny K. Ngo et al.   Redox Biology

Validation of the Italian version of the Movement Disorder Society—Unified Parkinson’s Disease Rating Scale

(2012) Angelo Antonini et al.   NEUROLOGICAL SCIENCES

Microvesicles are messengers

(2011) Jürg A. Schifferli   Seminars in Immunopathology

Systematic review of levodopa dose equivalency reporting in Parkinson's disease

(2010) Claire L. Tomlinson et al.   MOVEMENT DISORDERS

Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease

(2008) Shaji Theodore et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Assessment of PLSDA cross validation

(2008) Johan A. Westerhuis et al.   Metabolomics

Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons

(2008) Eric J. Benner et al.   PLoS One

Complex I deficiency in Parkinson's disease frontal cortex

(2007) W. Davis Parker et al.   BRAIN RESEARCH