Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis

Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Management of Rheumatoid Arthritis

(2018) Ozlem Akgul et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors

(2018) Giulia Bononi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Stealth and Cationic Nanoliposomes as Drug Delivery Systems to Increase Andrographolide BBB Permeability

(2018) Vieri Piazzini et al.   Pharmaceutics

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis

(2017) Silvia Bua et al.   JOURNAL OF MEDICINAL CHEMISTRY

Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis

(2017) Peter C. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis

(2017) Noha A. Yousri et al.   Scientific Reports

EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update

(2016) R Agca et al.   ANNALS OF THE RHEUMATIC DISEASES

An update on the up and coming therapies to treat osteoarthritis, a multifaceted disease

(2016) Jorge A. Roman-Blas et al.   EXPERT OPINION ON PHARMACOTHERAPY

Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium

(2016) Francesca Margheri et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Acute effect of Capparis spinosa root extracts on rat articular pain

(2016) Mario Maresca et al.   JOURNAL OF ETHNOPHARMACOLOGY

Paracetamol: not as safe as we thought? A systematic literature review of observational studies

(2015) Emmert Roberts et al.   ANNALS OF THE RHEUMATIC DISEASES

A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

(2015) Fabrizio Carta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors

(2015) Lorenzo Di Cesare Mannelli et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Hyaluronan molecular weight distribution is associated with the risk of knee osteoarthritis progression

(2015) P.A. Band et al.   OSTEOARTHRITIS AND CARTILAGE

Relative benefit-risk comparing diclofenac to other traditional non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors in patients with osteoarthritis or rheumatoid arthritis: a network meta-analysis

(2015) Anneloes van Walsem et al.   ARTHRITIS RESEARCH & THERAPY

Delay of Morphine Tolerance by Palmitoylethanolamide

(2015) Lorenzo Di Cesare Mannelli et al.   Biomed Research International

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

(2015) Jasvinder A. Singh et al.   Arthritis & Rheumatology

Strategy to provide a useful solution to effective delivery of dihydroartemisinin: Development, characterization and in vitro studies of liposomal formulations

(2014) Chiara Righeschi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

(2014) Lieselotte Vande Walle et al.   NATURE

Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment

(2013) A. Fakhari et al.   Acta Biomaterialia

Antiglaucoma carbonic anhydrase inhibitors: a patent review

(2013) Emanuela Masini et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Antiobesity carbonic anhydrase inhibitors: a literature and patent review

(2013) Andrea Scozzafava et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)

(2013) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats

(2013) Lorenzo Di Cesare Mannelli et al.   MEDIATORS OF INFLAMMATION

Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction

(2012) Yabing Zheng et al.   BMC MUSCULOSKELETAL DISORDERS

Carbonic Anhydrases III and IV Autoantibodies in Rheumatoid Arthritis, Systemic Lupus Erythematosus, Diabetes, Hypertensive Renal Disease, and Heart Failure

(2012) Chengeng Liu et al.   Clinical & Developmental Immunology

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Evaluation of complete Freund’s adjuvant-induced arthritis in a Wistar rat model

(2012) U. Snekhalatha et al.   ZEITSCHRIFT FUR RHEUMATOLOGIE

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

(2011) Y. Lou et al.   CANCER RESEARCH

Salvianolic acid B and its liposomal formulations: Anti-hyperalgesic activity in the treatment of neuropathic pain

(2011) Benedetta Isacchi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Increased expression of carbonic anhydrase I in the synovium of patients with ankylosing spondylitis

(2010) Xiaotian Chang et al.   BMC MUSCULOSKELETAL DISORDERS

Adverse event profile of tramadol in recent clinical studies of chronic osteoarthritis pain

(2009) Paul C. Langley et al.   CURRENT MEDICAL RESEARCH AND OPINION

Oxaliplatin-induced neuropathy in the rat: Involvement of oxalate in cold hyperalgesia but not mechanical allodynia

(2009) Mariko Sakurai et al.   PAIN

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY