Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1

Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1

(2018) Julie Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Chemokine–Receptor Interactions and Functions

(2017) Martin Stone   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of Regulation of the Chemokine-Receptor Network

(2017) Martin Stone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemokine isoforms and processing in inflammation and immunity

(2017) Paul Proost et al.   JOURNAL OF AUTOIMMUNITY

Ticks from diverse genera encode chemokine-inhibitory evasin proteins

(2017) Jenni Hayward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2

(2017) Zil E. Huma et al.   Science Signaling

Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2

(2017) Zil E. Huma et al.   Science Signaling

Biased Signaling at Chemokine Receptors

(2015) Jenny Corbisier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

(2015) L. Qin et al.   SCIENCE

Functional Interaction between Angiotensin II Receptor Type 1 and Chemokine (C-C Motif) Receptor 2 with Implications for Chronic Kidney Disease

(2015) Mohammed Akli Ayoub et al.   PLoS One

Internalization of the chemokine receptor CCR4 can be evoked by orthosteric and allosteric receptor antagonists

(2014) Laura Ajram et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Biased Agonism as a Mechanism for Differential Signaling by Chemokine Receptors

(2013) Sudarshan Rajagopal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine receptor CCR1 antagonist CCX354-C treatment for rheumatoid arthritis: CARAT-2, a randomised, placebo controlled clinical trial

(2012) Paul P Tak et al.   ANNALS OF THE RHEUMATIC DISEASES

Design and Receptor Interactions of Obligate Dimeric Mutant of Chemokine Monocyte Chemoattractant Protein-1 (MCP-1)

(2012) Joshua H. Y. Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Simple Method for Quantifying Functional Selectivity and Agonist Bias

(2011) Terry Kenakin et al.   ACS Chemical Neuroscience

Pharmacological characterization of a small-molecule agonist for the chemokine receptor CXCR3

(2011) DJ Scholten et al.   BRITISH JOURNAL OF PHARMACOLOGY

CCR1 as a target for multiple myeloma

(2011) Sonia Vallet et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Therapeutic potential of CCR1 antagonists for multiple myeloma

(2011) Angela R Karash et al.   Future Medicinal Chemistry

Deficiency of Chemokine Receptor CCR1 Causes Osteopenia Due to Impaired Functions of Osteoclasts and Osteoblasts

(2010) Akiyoshi Hoshino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers

(2009) Bettye Hollins et al.   CELLULAR SIGNALLING

Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands

(2009) D. A. Zidar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA