Lauric acid induce cell death in colon cancer cells mediated by the epidermal growth factor receptor downregulation: An in silico and in vitro study

Health impacts of different edible oils prepared from coconut (Cocos nucifera): A comprehensive review

(2018) Arunaksharan Narayanankutty et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Non-polar lipid carbonyls of thermally oxidized coconut oil induce hepatotoxicity mediated by redox imbalance

(2018) Arunaksharan Narayanankutty et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

CHARMM-GUI ligand reader and modeler for CHARMM force field generation of small molecules

(2017) Seonghoon Kim et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

(2017) Pablo Angulo et al.   Journal of Hematology & Oncology

Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats

(2017) Arunaksharan Narayanankutty et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer

(2017) Yasuyuki Okada et al.   MOLECULAR CANCER RESEARCH

Coconut phytocompounds inhibits polyol pathway enzymes: Implication in prevention of microvascular diabetic complications

(2017) Devi Lekshmi Sheela et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Epithelial Mesenchymal Transition in Cancer Progression: Prev entive Phytochemicals

(2017) Soorya P. Illam et al.   Recent Patents on Anti-Cancer Drug Discovery

Polyphenols of virgin coconut oil prevent pro-oxidant mediated cell death

(2017) Soorya Parathodi Illam et al.   TOXICOLOGY MECHANISMS AND METHODS

Remodeling of energy metabolism by a ketone body and medium-chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

(2017) Yui Kadochi et al.   Oncology Letters

Inhibition of cell cycle progression by the hydroxytyrosol–cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells

(2017) Erika Terzuoli et al.   Oncotarget

Polyphenols of virgin coconut oil prevent pro-oxidant mediated cell death

(2017) Soorya Parathodi Illam et al.   TOXICOLOGY MECHANISMS AND METHODS

EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide

(2017) Nabarun Roy et al.   Interdisciplinary Sciences-Computational Life Sciences

Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitors

(2017) David Lagorce et al.   Scientific Reports

High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer

(2016) Reilly T. Enos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia

(2016) Yongqiang Chen et al.   Autophagy

3-D structural interactions and quantitative structural toxicity studies of tyrosine derivatives intended for safe potent inflammation treatment

(2016) Ayarivan Puratchikody et al.   Chemistry Central Journal

Deep fried edible oils disturb hepatic redox equilibrium and heightens lipotoxicity and hepatosteatosis in male Wistar rats

(2016) A Narayanankutty et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Lauric Acid Stimulates Ketone Body Production in the KT-5 Astrocyte Cell Line

(2016) Yudai Nonaka et al.   Journal of Oleo Science

A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803

(2016) Donna Niedzwiecki et al.   ONCOLOGIST

In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil

(2016) Devi Lekshmi Sheela et al.   PLANT FOODS FOR HUMAN NUTRITION

Bcl-xL is an oncogenic driver in colorectal cancer

(2016) Anna-Lena Scherr et al.   Cell Death & Disease

EGFR Cell Survival Signaling Requires Phosphatidylcholine Biosynthesis

(2016) M. Crook et al.   G3-Genes Genomes Genetics

Overall survival benefits of first-line EGFR tyrosine kinase inhibitors in EGFR-mutated non-small-cell lung cancers: a systematic review and meta-analysis

(2015) Feng-Che Kuan et al.   BRITISH JOURNAL OF CANCER

Virgin coconut oil maintains redox status and improves glycemic conditions in high fructose fed rats

(2015) Arunaksharan Narayanankutty et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Estrogen Receptors and Their Implications in Colorectal Carcinogenesis

(2015) Francesco Caiazza et al.   Frontiers in Oncology

Induction of Apoptosis by the Medium-Chain Length Fatty Acid Lauric Acid in Colon Cancer Cells due to Induction of Oxidative Stress

(2013) J.K. Fauser et al.   CHEMOTHERAPY

Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike?

(2013) Wasif Saif   Cancer Management and Research

Down-regulation of Epidermal Growth Factor Receptor by Selective Expansion of a 5'-End Regulatory Dinucleotide Repeat in Colon Cancer with Microsatellite Instability

(2009) S. Baranovskaya et al.   CLINICAL CANCER RESEARCH

Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells

(2009) C. Morales et al.   MOLECULAR CANCER THERAPEUTICS

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL