Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system

Gene Therapy to Enhance Bone and Cartilage Repair in Orthopaedic Surgery

(2018) Sofia Bougioukli et al.   CURRENT GENE THERAPY

Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2–Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow

(2018) Sofia Bougioukli et al.   HUMAN GENE THERAPY

Cryopreservation of Human Adipose-Derived Stem Cells for Use in Ex Vivo Regional Gene Therapy for Bone Repair

(2018) Venus Vakhshori et al.   Human Gene Therapy Methods

Development of a Cell-Based Gene Therapy Approach to Selectively Turn Off Bone Formation

(2017) Pedro Alvarez-Urena et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Improving the safety of T-Cell therapies using an inducible caspase-9 gene

(2016) Xiaoou Zhou et al.   EXPERIMENTAL HEMATOLOGY

Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation

(2016) Xiaoou Zhou et al.   MOLECULAR THERAPY

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

(2015) X. Zhou et al.   BLOOD

Biodistribution of LV-TSTA Transduced Rat Bone Marrow Cells Used for “Ex-vivo” Regional Gene Therapy for Bone Repair

(2015) Farhang Alaee et al.   CURRENT GENE THERAPY

The role of transduced bone marrow cells overexpressing BMP-2 in healing critical-sized defects in a mouse femur

(2015) M Pensak et al.   GENE THERAPY

An Inducible Caspase-9 Suicide Gene to Improve the Safety of Therapy Using Human Induced Pluripotent Stem Cells

(2015) Shigeki Yagyu et al.   MOLECULAR THERAPY

Gene therapy approaches to regenerating the musculoskeletal system

(2015) Christopher H. Evans et al.   Nature Reviews Rheumatology

Bone morphogenetic protein 2 gene transduction enhances the osteogenic potential of human urine-derived stem cells

(2015) Junjie Guan et al.   Stem Cell Research & Therapy

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

(2014) X. Zhou et al.   BLOOD

Adverse Events After Recombinant Human BMP2 in Nonspinal Orthopaedic Procedures

(2012) Emily Jane Woo   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The Osteogenic Study of Tissue Engineering Bone with BMP2 and BMP7 Gene-Modified Rat Adipose-Derived Stem Cell

(2012) Wang Qing et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

“Same Day” Ex-vivo Regional Gene Therapy: A Novel Strategy to Enhance Bone Repair

(2011) Mandeep S Virk et al.   MOLECULAR THERAPY

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned

(2011) Eugene J. Carragee et al.   Spine Journal

An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies

(2010) Carlos Almeida Ramos et al.   STEM CELLS