Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD
Authors
Keywords
-
Journal
Current Atherosclerosis Reports
Volume 21, Issue 8, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-21
DOI
10.1007/s11883-019-0791-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease
- (2019) Brian A. Ference et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- APOC3Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular RiskHighlights
- (2018) Anders B. Wulff et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- RNA-Targeted Therapeutics
- (2018) Stanley T. Crooke et al. Cell Metabolism
- An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
- (2018) Adil Mardinoglu et al. Cell Metabolism
- Sialylated isoforms of apolipoprotein C-III and plasma lipids in subjects with coronary artery disease
- (2018) Oliviero Olivieri et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism
- (2018) Bastian Ramms et al. CURRENT OPINION IN LIPIDOLOGY
- Molecular actions of PPARα in lipid metabolism and inflammation
- (2018) Nadia Bougarne et al. ENDOCRINE REVIEWS
- Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths
- (2018) Maija Ruuth et al. EUROPEAN HEART JOURNAL
- Treatment with Volanesorsen (VLN) Reduced Triglycerides and Pancreatitis in Patients with FCS and sHTG vs Placebo: Results of the APPROACH and COMPASS †
- (2018) Andres Gelrud et al. Journal of Clinical Lipidology
- Effect of statin therapy on plasma apolipoprotein CIII concentrations: A systematic review and meta-analysis of randomized controlled trials
- (2018) Amirhossein Sahebkar et al. Journal of Clinical Lipidology
- Characterizing familial chylomicronemia syndrome: Baseline data of the APPROACH study
- (2018) Dirk J. Blom et al. Journal of Clinical Lipidology
- INHIBITION OF APOLIPOPROTEIN C-III WITH GALNAC CONJUGATED ANTISENSE DRUG POTENTLY LOWERS FASTING SERUM APOLIPOPROTEIN C-III AND TRIGLYCERIDE LEVELS IN HEALTHY VOLUNTEERS WITH ELEVATED TRIGLYCERIDES
- (2018) Veronica J. Alexander et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2ʹ-MOE-Modified Antisense Oligonucleotide
- (2018) Padmakumar Narayanan et al. TOXICOLOGICAL SCIENCES
- Journey of siRNA: Clinical Developments and Targeted Delivery
- (2018) Rahul R. Nikam et al. Nucleic Acid Therapeutics
- GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics
- (2018) Aaron D. Springer et al. Nucleic Acid Therapeutics
- Effect of protein, unsaturated fat, and carbohydrate intakes on plasma apolipoprotein B and VLDL and LDL containing apolipoprotein C-III: results from the OmniHeart Trial
- (2018) Jeremy D Furtado et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Effect of omega-3 supplements on plasma apolipoprotein C-III concentrations: a systematic review and meta-analysis of randomized controlled trials
- (2018) Amirhossein Sahebkar et al. ANNALS OF MEDICINE
- Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
- (2018) NEW ENGLAND JOURNAL OF MEDICINE
- Effects of APOC3 Heterozygous Deficiency on Plasma Lipid and Lipoprotein Metabolism
- (2018) Gissette Reyes-Soffer et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program
- (2018) Derek Klarin et al. NATURE GENETICS
- Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
- (2018) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies
- (2018) Vivian L Choo et al. BMJ-British Medical Journal
- Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity
- (2017) Jean-Marc Schwarz et al. GASTROENTEROLOGY
- Changes in low-density lipoprotein size phenotypes associate with changes in apolipoprotein C-III glycoforms after dietary interventions
- (2017) Saulo Mendoza et al. Journal of Clinical Lipidology
- Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity
- (2017) M.-R. Taskinen et al. JOURNAL OF INTERNAL MEDICINE
- The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation
- (2017) Meenakshi Sundaram et al. JOURNAL OF LIPID RESEARCH
- Aromatic residues in the C terminus of apolipoprotein C-III mediate lipid binding and LPL inhibition
- (2017) Nathan L. Meyers et al. JOURNAL OF LIPID RESEARCH
- Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review
- (2017) Jan Oscarsson et al. Lipids in Health and Disease
- Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity
- (2017) Danish Saleheen et al. NATURE
- Exome-wide association study of plasma lipids in >300,000 individuals
- (2017) Dajiang J Liu et al. NATURE GENETICS
- A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels
- (2017) Sumeet A Khetarpal et al. NATURE MEDICINE
- Increasing Lipolysis and Reducing Atherosclerosis
- (2017) Alan R. Tall NEW ENGLAND JOURNAL OF MEDICINE
- Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
- (2017) Karsten Schmidt et al. NUCLEIC ACIDS RESEARCH
- Omega-3 Fatty Acids and Cardiovascular Disease: Summary of the 2016 Agency of Healthcare Research and Quality Evidence Review
- (2017) Ethan Balk et al. Nutrients
- Why Is Apolipoprotein CIII Emerging as a Novel Therapeutic Target to Reduce the Burden of Cardiovascular Disease?
- (2016) Marja-Riitta Taskinen et al. Current Atherosclerosis Reports
- Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes
- (2016) Andres Digenio et al. DIABETES CARE
- ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors
- (2016) Philip L.S.M. Gordts et al. JOURNAL OF CLINICAL INVESTIGATION
- Icosapent ethyl (eicosapentaenoic acid ethyl ester): Effects on plasma apolipoprotein C-III levels in patients from the MARINE and ANCHOR studies
- (2016) Christie M. Ballantyne et al. Journal of Clinical Lipidology
- The effect of omega-3 carboxylic acids on apolipoprotein CIII−containing lipoproteins in severe hypertriglyceridemia
- (2016) Allyson M. Morton et al. Journal of Clinical Lipidology
- Reduction in lipoprotein-associated apoC-III levels following volanesorsen therapy: phase 2 randomized trial results
- (2016) Xiaohong Yang et al. JOURNAL OF LIPID RESEARCH
- A dose-response study of consuming high-fructose corn syrup–sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults
- (2015) Kimber L Stanhope et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal ObesitySignificance
- (2015) Jan Borén et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- New insights into the pathophysiology of dyslipidemia in type 2 diabetes
- (2015) Marja-Riitta Taskinen et al. ATHEROSCLEROSIS
- The crucial roles of apolipoproteins E and C-III in apoB lipoprotein metabolism in normolipidemia and hypertriglyceridemia
- (2015) Frank M. Sacks CURRENT OPINION IN LIPIDOLOGY
- Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial
- (2015) Richard L. Dunbar et al. Lipids in Health and Disease
- Development of multiplex mass spectrometric immunoassay for detection and quantification of apolipoproteins C-I, C-II, C-III and their proteoforms
- (2015) Olgica Trenchevska et al. METHODS
- Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
- (2015) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rare Variant APOC3 R19X Is Associated With Cardio-Protective Profiles in a Diverse Population-Based Survey as Part of the Epidemiologic Architecture for Genes Linked to Environment Study
- (2014) D. C. Crawford et al. Circulation-Cardiovascular Genetics
- Inhibition of ApoCIII
- (2014) Sophie J. Bernelot Moens et al. CURRENT OPINION IN LIPIDOLOGY
- Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
- (2014) Anders Berg Jørgensen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting APOC3 in the Familial Chylomicronemia Syndrome
- (2014) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans
- (2013) Mark J. Graham et al. CIRCULATION RESEARCH
- Two novel mutations in apolipoprotein C3 underlie atheroprotective lipid profiles in families
- (2013) A.E. Bochem et al. CLINICAL GENETICS
- A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates
- (2013) Ioanna Tachmazidou et al. Nature Communications
- Implementing a successful data-management framework: the UK10K managed access model
- (2013) Dawn Muddyman et al. Genome Medicine
- Effect of Combination Therapy With Fenofibrate and Simvastatin on Postprandial Lipemia in the ACCORD Lipid Trial
- (2012) G. Reyes-Soffer et al. DIABETES CARE
- Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men
- (2012) N Faghihnia et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Effects of prescription omega-3-acid ethyl esters, coadministered with atorvastatin, on circulating levels of lipoprotein particles, apolipoprotein CIII, and lipoprotein-associated phospholipase A2 mass in men and women with mixed dyslipidemia
- (2011) Kevin C. Maki et al. Journal of Clinical Lipidology
- Silencing disease genes in the laboratory and the clinic
- (2011) Jonathan K Watts et al. JOURNAL OF PATHOLOGY
- Transcriptional Activation of Apolipoprotein CIII Expression by Glucose May Contribute to Diabetic Dyslipidemia
- (2010) Sandrine Caron et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Regulation of Hepatic ApoC3 Expression by PGC-1β Mediates Hypolipidemic Effect of Nicotinic Acid
- (2010) Carlos Hernandez et al. Cell Metabolism
- Apolipoprotein C-III and the Metabolic Basis for Hypertriglyceridemia and the Dense Low-Density Lipoprotein Phenotype
- (2010) Chunyu Zheng et al. CIRCULATION
- Origins and Mechanisms of miRNAs and siRNAs
- (2009) Richard W. Carthew et al. CELL
- ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan
- (2009) A. Hiukka et al. DIABETES
- Triglyceride-Rich Lipoprotein-Associated Apolipoprotein C-III Production Is Stimulated by Plasma Free Fatty Acids in Humans
- (2008) Mirjana Pavlic et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Atorvastatin and Fenofibrate Have Comparable Effects on VLDL-Apolipoprotein C-III Kinetics in Men With the Metabolic Syndrome
- (2008) Dick C. Chan et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Overproduction of Very Low–Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome
- (2008) Martin Adiels et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Dose-Dependent Effect of Rosuvastatin on VLDL-Apolipoprotein C-III Kinetics in the Metabolic Syndrome
- (2008) E. M.M. Ooi et al. DIABETES CARE
- Structure and Dynamics of Human Apolipoprotein CIII
- (2008) Chinthaka Saneth Gangabadage et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection
- (2008) T. I. Pollin et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started