The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation

D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile

(2016) Sophie Valleix et al.   Nature Communications

Targeted next-generation sequencing in monogenic dyslipidemias

(2015) Robert A. Hegele et al.   CURRENT OPINION IN LIPIDOLOGY

LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias

(2014) Christopher T. Johansen et al.   JOURNAL OF LIPID RESEARCH

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

(2013) Mark J. Graham et al.   CIRCULATION RESEARCH

Apolipoprotein C-III and hepatic triglyceride-rich lipoprotein production

(2012) Zemin Yao et al.   CURRENT OPINION IN LIPIDOLOGY

Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance

(2011) Hui-Young Lee et al.   HEPATOLOGY

Missense Mutation inAPOC3within the C-terminal Lipid Binding Domain of Human ApoC-III Results in Impaired Assembly and Secretion of Triacylglycerol-rich Very Low Density Lipoproteins

(2011) Wen Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Activation of Apolipoprotein CIII Expression by Glucose May Contribute to Diabetic Dyslipidemia

(2010) Sandrine Caron et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Functional analysis of the missenseAPOC3mutation Ala23Thr associated with human hypotriglyceridemia

(2010) Meenakshi Sundaram et al.   JOURNAL OF LIPID RESEARCH

Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions

(2009) M. Sundaram et al.   JOURNAL OF LIPID RESEARCH

Structure and Dynamics of Human Apolipoprotein CIII

(2008) Chinthaka Saneth Gangabadage et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

(2008) T. I. Pollin et al.   SCIENCE