Imaging Spatiotemporal Activities of ZAP-70 in Live T Cells Using a FRET-Based Biosensor

ROZA-XL, an improved FRET based biosensor with an increased dynamic range for visualizing Zeta Associated Protein 70 kD (ZAP-70) tyrosine kinase activity in live T cells

(2015) Sophie Cadra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex

(2015) Baoyu Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A FRET-Based Biosensor for Imaging SYK Activities in Living Cells

(2011) Xue Xiang et al.   Cellular and Molecular Bioengineering

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

(2011) Ning Jiang et al.   IMMUNITY

Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer

(2011) Jihye Seong et al.   Nature Communications

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

(2010) Jun Huang et al.   NATURE

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity

(2010) Byron B Au-Yeung et al.   NATURE IMMUNOLOGY

ZAP-70: An Essential Kinase in T-cell Signaling

(2010) H. Wang et al.   Cold Spring Harbor Perspectives in Biology

The structure, regulation, and function of ZAP-70

(2009) Byron B. Au-Yeung et al.   IMMUNOLOGICAL REVIEWS

The T-cell-receptor signaling network

(2009) M. Huse   JOURNAL OF CELL SCIENCE

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

(2009) Björn F Lillemeier et al.   NATURE IMMUNOLOGY

T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation

(2008) Hai-Tao He et al.   EMBO REPORTS

A Novel ZAP-70 Dependent FRET Based Biosensor Reveals Kinase Activity at both the Immunological Synapse and the Antisynapse

(2008) Clotilde Randriamampita et al.   PLoS One

The Spatiotemporal Pattern of Src Activation at Lipid Rafts Revealed by Diffusion-Corrected FRET Imaging

(2008) Shaoying Lu et al.   PLoS Computational Biology