Progress in understanding mitochondrial calcium uniporter complex‐mediated calcium signalling: A potential target for cancer treatment
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Title
Progress in understanding mitochondrial calcium uniporter complex‐mediated calcium signalling: A potential target for cancer treatment
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 176, Issue 9, Pages 1190-1205
Publisher
Wiley
Online
2019-02-26
DOI
10.1111/bph.14632
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Note: Only part of the references are listed.- MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation
- (2018) Tingting Ren et al. ANTIOXIDANTS & REDOX SIGNALING
- Targeting Orai1-mediated store-operated calcium entry by RP4010 for anti-tumor activity in esophagus squamous cell carcinoma
- (2018) Chaochu Cui et al. CANCER LETTERS
- RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+Uptake and Promotes Colorectal Oncogenesis
- (2018) Fanxin Zeng et al. CANCER RESEARCH
- MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake
- (2018) Maria Patron et al. CELL DEATH AND DIFFERENTIATION
- Autophagy: Mitochondria encaged
- (2018) Paulina Strzyz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- X-ray and cryo-EM structures of the mitochondrial calcium uniporter
- (2018) Chao Fan et al. NATURE
- Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
- (2018) Rozbeh Baradaran et al. NATURE
- MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+
- (2018) Kimberli J. Kamer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening
- (2017) Daniela M. Arduino et al. MOLECULAR CELL
- Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
- (2017) Zhiwei Dong et al. MOLECULAR CELL
- The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
- (2017) Simon D Harding et al. NUCLEIC ACIDS RESEARCH
- MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells
- (2017) T Ren et al. ONCOGENE
- Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy
- (2017) Tania Zaglia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter
- (2017) Chan Cao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial calcium uniporter as a target of microRNA-340 and promoter of metastasis via enhancing the Warburg effect
- (2017) Changhui Yu et al. Oncotarget
- MICU2 Restricts Spatial Crosstalk between InsP 3 R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU
- (2017) Riley Payne et al. Cell Reports
- Targeting calcium signaling in cancer therapy
- (2017) Chaochu Cui et al. Acta Pharmaceutica Sinica B
- The apoptotic members CD95, BclxL and Bcl-2 cooperate to promote cell migration by inducing Ca2+ flux from the endoplasmic reticulum to mitochondria
- (2016) A Fouqué et al. CELL DEATH AND DIFFERENTIATION
- The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α
- (2016) Anna Tosatto et al. EMBO Molecular Medicine
- Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition
- (2016) Dipayan Chaudhuri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca2+ uptake in immortalized cells
- (2016) Corina T. Madreiter-Sokolowski et al. Nature Communications
- MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics
- (2016) Dhanendra Tomar et al. Cell Reports
- Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex
- (2016) Ming-Feng Tsai et al. eLife
- Mitochondrial Ca2+ uniporter is critical for store-operated Ca2+ entry-dependent breast cancer cell migration
- (2015) Shihao Tang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitofusin-2 triggers mitochondria Ca2+ influx from the endoplasmic reticulum to induce apoptosis in hepatocellular carcinoma cells
- (2015) Weilin Wang et al. CANCER LETTERS
- CCDC90A (MCUR1) Is a Cytochrome c Oxidase Assembly Factor and Not a Regulator of the Mitochondrial Calcium Uniporter
- (2015) Vincent Paupe et al. Cell Metabolism
- MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter
- (2015) Horia Vais et al. Cell Metabolism
- The Ca2+-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca2+ Uptake
- (2015) Carmelina Petrungaro et al. Cell Metabolism
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Targeting mitochondria metabolism for cancer therapy
- (2015) Samuel E Weinberg et al. Nature Chemical Biology
- Adrenergic Signaling Regulates Mitochondrial Ca2+ Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca2+ Uniporter
- (2014) Jin O-Uchi et al. ANTIOXIDANTS & REDOX SIGNALING
- MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity
- (2014) Maria Patron et al. MOLECULAR CELL
- Mitochondrial calcium uniporter silencing potentiates caspase-independent cell death in MDA-MB-231 breast cancer cells
- (2013) Merril C. Curry et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dynamics of mitochondrial Ca2+uptake in MICU1-knockdown cells
- (2013) Sergio de la Fuente et al. BIOCHEMICAL JOURNAL
- Minocycline: far beyond an antibiotic
- (2013) N Garrido-Mesa et al. BRITISH JOURNAL OF PHARMACOLOGY
- MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
- (2013) György Csordás et al. Cell Metabolism
- The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
- (2013) Anna Raffaello et al. EMBO JOURNAL
- Mitochondrial modulation decreases the bortezomib-resistance in multiple myeloma cells
- (2013) I.S. Song et al. INTERNATIONAL JOURNAL OF CANCER
- Probing Novel Roles of the Mitochondrial Uniporter in Ovarian Cancer Cells Using Nanoparticles
- (2013) Rochelle R. Arvizo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications
- (2013) Saverio Marchi et al. JOURNAL OF PHYSIOLOGY-LONDON
- MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
- (2013) Molly Plovanich et al. PLoS One
- EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
- (2013) Y. Sancak et al. SCIENCE
- Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter
- (2013) Justin Schwartz et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- MCU encodes the pore conducting mitochondrial calcium currents
- (2013) Dipayan Chaudhuri et al. eLife
- MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
- (2012) Karthik Mallilankaraman et al. CELL
- Mitochondrial Ca2+ and apoptosis
- (2012) Carlotta Giorgi et al. CELL CALCIUM
- Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
- (2012) Saverio Marchi et al. CURRENT BIOLOGY
- Effective Killing of Leukemia Cells by the Natural Product OSW-1 through Disruption of Cellular Calcium Homeostasis
- (2012) Celia Garcia-Prieto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interplay of reactive oxygen species, intracellular Ca2+and mitochondrial homeostasis in the apoptosis of prostate cancer cells by deoxypodophyllotoxin
- (2012) Kwang-Youn Kim et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- CaMKII determines mitochondrial stress responses in heart
- (2012) Mei-ling A. Joiner et al. NATURE
- MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
- (2012) Karthik Mallilankaraman et al. NATURE CELL BIOLOGY
- Mitochondria as sensors and regulators of calcium signalling
- (2012) Rosario Rizzuto et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Investigation of Mitochondrial Dysfunction by Sequential Microplate-Based Respiration Measurements from Intact and Permeabilized Neurons
- (2012) Pascaline Clerc et al. PLoS One
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- (2012) Francesca Fieni et al. Nature Communications
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis
- (2011) Andrea Rasola et al. CELL CALCIUM
- After half a century mitochondrial calcium in- and efflux machineries reveal themselves
- (2011) Ilaria Drago et al. EMBO JOURNAL
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- KB-R7943, an inhibitor of the reverse Na+/Ca2+ exchanger, blocks N-methyl-D-aspartate receptor and inhibits mitochondrial complex I
- (2010) Tatiana Brustovetsky et al. BRITISH JOURNAL OF PHARMACOLOGY
- Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
- (2010) César Cárdenas et al. CELL
- MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
- (2010) Fabiana Perocchi et al. NATURE
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis
- (2009) Shengyu Yang et al. CANCER CELL
- A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
- (2008) David J. Pagliarini et al. CELL
- Mitochondrial complex III regulates hypoxic activation of HIF
- (2008) T Klimova et al. CELL DEATH AND DIFFERENTIATION
- Mitochondria: The Hub of Cellular Ca2+ Signaling
- (2008) György Szabadkai et al. PHYSIOLOGY
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