Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
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Title
Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
Authors
Keywords
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Journal
BMC MUSCULOSKELETAL DISORDERS
Volume 20, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-10
DOI
10.1186/s12891-019-2595-z
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- TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?
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- (2015) S. Larsson et al. OSTEOARTHRITIS AND CARTILAGE
- Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen
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- (2013) T. Neogi OSTEOARTHRITIS AND CARTILAGE
- Tanezumab Reduces Osteoarthritic Knee Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial
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- Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain
- (2011) Patrick W. Mantyh et al. ANESTHESIOLOGY
- Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose-escalation, placebo-controlled study
- (2011) H. Nagashima et al. OSTEOARTHRITIS AND CARTILAGE
- Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee
- (2010) Nancy E. Lane et al. NEW ENGLAND JOURNAL OF MEDICINE
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- Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis
- (2009) Christian Barthel et al. ARTHRITIS RESEARCH & THERAPY
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