Nerve Growth Factor Regulation by TNF-αand IL-1βin Synovial Macrophages and Fibroblasts in Osteoarthritic Mice

CD11c+macrophages and levels of TNF-α and MMP-3 are increased in synovial and adipose tissues of osteoarthritic mice with hyperlipidaemia

(2015) K. Uchida et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Synovial macrophage-derived IL-1βregulates the calcitonin receptor in osteoarthritic mice

(2015) S. Takano et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms

(2015) M. A. Eskander et al.   JOURNAL OF NEUROSCIENCE

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

(2015) E.N. Blaney Davidson et al.   OSTEOARTHRITIS AND CARTILAGE

Efficacy of Direct Injection of Etanercept into Knee Joints for Pain in Moderate and Severe Knee Osteoarthritis

(2015) Seiji Ohtori et al.   YONSEI MEDICAL JOURNAL

Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain

(2014) Emilie Pecchi et al.   ARTHRITIS RESEARCH & THERAPY

Structural Associations of Symptomatic Knee Osteoarthritis

(2014) Laura A. Stoppiello et al.   Arthritis & Rheumatology

Increase of Circulating CD11b+Gr1+ cells and Recruitment into the Synovium in Osteoarthritic Mice with Hyperlipidemia

(2013) Kentaro Uchida et al.   EXPERIMENTAL ANIMALS

Interleukin-17–producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity

(2013) Hye Young Kim et al.   NATURE MEDICINE

Nerve growth factor: an update on the science and therapy

(2013) M.F. Seidel et al.   OSTEOARTHRITIS AND CARTILAGE

The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study

(2013) Y. Shimura et al.   OSTEOARTHRITIS AND CARTILAGE

Efficacy, safety, and tolerability of fulranumab, an anti-nerve growth factor antibody, in the treatment of patients with moderate to severe osteoarthritis pain

(2013) Panna Sanga et al.   PAIN

Characterization of nerve growth factor-induced mechanical and thermal hypersensitivity in rats

(2012) C.D. Mills et al.   EUROPEAN JOURNAL OF PAIN

Tanezumab Reduces Osteoarthritic Knee Pain: Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial

(2012) Mark T. Brown et al.   JOURNAL OF PAIN

Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

(2011) Sumihisa Orita et al.   BMC MUSCULOSKELETAL DISORDERS

The role of proinflammatory cytokines in the generation and maintenance of joint pain

(2010) H-G. Schaible et al.   Annals of the New York Academy of Sciences

Signaling pathways that mediate nerve growth factor-induced increase in expression and release of calcitonin gene-related peptide from sensory neurons

(2010) K.A. Park et al.   NEUROSCIENCE

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

(2010) Nancy E. Lane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain

(2010) N. Schuelert et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritic Changes of the Patellofemoral Joint in STR/OrtCrlj Mice Are the Earliest Detectable Changes and may be Caused by Internal Tibial Torsion

(2009) Kouji Naruse et al.   CONNECTIVE TISSUE RESEARCH

OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

(2008) W. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE