Development of a novel, high‐throughput screening tool for efficient perfusion‐based cell culture process development

Perfusion mammalian cell culture for recombinant protein manufacturing – A critical review

(2018) Jean-Marc Bielser et al.   BIOTECHNOLOGY ADVANCES

Process performance and product quality in an integrated continuous antibody production process

(2016) Daniel J. Karst et al.   BIOTECHNOLOGY AND BIOENGINEERING

Simultaneous monitoring of oxidation, deamidation, isomerization, and glycosylation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast tryptic digestion

(2016) Yi Wang et al.   mAbs

Continuous downstream processing for high value biological products: A Review

(2015) Andrew L. Zydney   BIOTECHNOLOGY AND BIOENGINEERING

Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development

(2015) Vijay Janakiraman et al.   BIOTECHNOLOGY PROGRESS

Development and application of a high-throughput platform for perfusion-based cell culture processes

(2015) Agata Villiger-Oberbek et al.   JOURNAL OF BIOTECHNOLOGY

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics

(2015) Richard S Rogers et al.   mAbs

Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality

(2014) William C. Yang et al.   BIOTECHNOLOGY PROGRESS

Novel platform technology for scale down and process optimisation for regenerative medicine

(2014) R. Drake et al.   CYTOTHERAPY

Automated disposable small scale reactor for high throughput bioprocess development: A proof of concept study

(2013) Rachel Bareither et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fed-batch and perfusion culture processes: Economic, environmental, and operational feasibility under uncertainty

(2012) James Pollock et al.   BIOTECHNOLOGY AND BIOENGINEERING

Advanced microscale bioreactor system: a representative scale-down model for bench-top bioreactors

(2012) Wei-Ting Hsu et al.   CYTOTECHNOLOGY

Estimating cell specific oxygen uptake and carbon dioxide production rates for mammalian cells in perfusion culture

(2011) Chetan T. Goudar et al.   BIOTECHNOLOGY PROGRESS

A review of advanced small-scale parallel bioreactor technology for accelerated process development: Current state and future need

(2010) Rachel Bareither et al.   BIOTECHNOLOGY PROGRESS

Bioreactor scale-up and oxygen transfer rate in microbial processes: An overview

(2008) Felix Garcia-Ochoa et al.   BIOTECHNOLOGY ADVANCES

Pharmaceutical Quality by Design: Product and Process Development, Understanding, and Control

(2008) Lawrence X. Yu   PHARMACEUTICAL RESEARCH