Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development

Application of bioreactor design principles and multivariate analysis for development of cell culture scale down models

(2014) Lia Tescione et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput miniaturized bioreactors for cell culture process development: Reproducibility, scalability, and control

(2014) Shahid Rameez et al.   BIOTECHNOLOGY PROGRESS

A practical strategy for using miniature chromatography columns in a standardized high-throughput workflow for purification development of monoclonal antibodies

(2014) John P. Welsh et al.   BIOTECHNOLOGY PROGRESS

Addition of Valproic Acid to CHO Cell Fed-Batch Cultures Improves Monoclonal Antibody Titers

(2014) William C. Yang et al.   MOLECULAR BIOTECHNOLOGY

The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4

(2013) Alvin W. Nienow et al.   BIOCHEMICAL ENGINEERING JOURNAL

Automated disposable small scale reactor for high throughput bioprocess development: A proof of concept study

(2013) Rachel Bareither et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of a scale down cell culture model using multivariate analysis as a qualification tool

(2013) Valerie Liu Tsang et al.   BIOTECHNOLOGY PROGRESS

Advanced microscale bioreactor system: a representative scale-down model for bench-top bioreactors

(2012) Wei-Ting Hsu et al.   CYTOTECHNOLOGY

Multivariate data analysis on historical IPV production data for better process understanding and future improvements

(2010) Yvonne E. Thomassen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Defining process design space for monoclonal antibody cell culture

(2010) Susan Fugett Abu-Absi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

(2010) Yao-Ming Huang et al.   BIOTECHNOLOGY PROGRESS

A review of advanced small-scale parallel bioreactor technology for accelerated process development: Current state and future need

(2010) Rachel Bareither et al.   BIOTECHNOLOGY PROGRESS

A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells

(2009) Rachel Legmann et al.   BIOTECHNOLOGY AND BIOENGINEERING

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Twenty-four well plate miniature bioreactor system as a scale-down model for cell culture process development

(2008) Aaron Chen et al.   BIOTECHNOLOGY AND BIOENGINEERING