Microfluidic and computational study of structural properties and resistance to flow of blood clots under arterial shear

Impact of Tissue Factor Localization on Blood Clot Structure and Resistance under Venous Shear

(2018) Vijay Govindarajan et al.   BIOPHYSICAL JOURNAL

Computational Study of Thrombus Formation and Clotting Factor Effects under Venous Flow Conditions

(2016) Vijay Govindarajan et al.   BIOPHYSICAL JOURNAL

In microfluidico: Recreating in vivo hemodynamics using miniaturized devices

(2016) Shu Zhu et al.   BIORHEOLOGY

Blood flow and mass transfer regulation of coagulation

(2016) Kuldeepsinh Rana et al.   BLOOD REVIEWS

Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces

(2016) Shu Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Computational modelling of clot development in patient-specific cerebral aneurysm cases

(2016) M. N. Ngoepe et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Ex vivo recapitulation of trauma-induced coagulopathy and preliminary assessment of trauma patient platelet function under flow using microfluidic technology

(2016) Ruizhi Li et al.   Journal of Trauma and Acute Care Surgery

Ex vivo recapitulation of trauma-induced coagulopathy and preliminary assessment of trauma patient platelet function under flow using microfluidic technology

(2016) Ruizhi Li et al.   Journal of Trauma and Acute Care Surgery

Fluid Mechanics of Blood Clot Formation

(2015) Aaron L. Fogelson et al.   Annual Review of Fluid Mechanics

Fibrin, γ′-Fibrinogen, and Transclot Pressure Gradient Control Hemostatic Clot Growth During Human Blood Flow Over a Collagen/Tissue Factor WoundSignificance

(2015) Ryan W. Muthard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow

(2015) S. Zhu et al.   BLOOD

A 3D model of thrombus formation in a stent-graft after implantation in the abdominal aorta

(2015) Andrzej Polanczyk et al.   JOURNAL OF BIOMECHANICS

Continuous Modeling of Arterial Platelet Thrombus Formation Using a Spatial Adsorption Equation

(2015) Evgenia S. Babushkina et al.   PLoS One

A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment

(2014) M. Tomaiuolo et al.   BLOOD

Kinetic model facilitates analysis of fibrin generation and its modulation by clotting factors: implications for hemostasis-enhancing therapies

(2014) Alexander Y. Mitrophanov et al.   Molecular BioSystems

Platelet Transport Rates and Binding Kinetics at High Shear over a Thrombus

(2013) David L. Bark et al.   BIOPHYSICAL JOURNAL

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

(2013) T. J. Stalker et al.   BLOOD

Sources of Variability in Platelet Accumulation on Type 1 Fibrillar Collagen in Microfluidic Flow Assays

(2013) Keith B. Neeves et al.   PLoS One

Thrombus Growth and Embolism on Tissue Factor-Bearing Collagen Surfaces Under Flow

(2012) Thomas V. Colace et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Influence of Hindered Transport on the Development of Platelet Thrombi Under Flow

(2012) Karin Leiderman et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse

(2012) J. D. WELSH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Simulated Surface-Induced Thrombin Generation in a Flow Field

(2011) S.W. Jordan et al.   BIOPHYSICAL JOURNAL

Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

(2011) K. R. Machlus et al.   BLOOD

A novel automated microchip flow-chamber system to quantitatively evaluate thrombus formation and antithrombotic agents under blood flow conditions

(2011) K. HOSOKAWA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Transport-Reaction Model of Mural Thrombogenesis: Comparisons of Mathematical Model Predictions and Results from Baboon Models

(2010) Sandra Rugonyi et al.   ANNALS OF BIOMEDICAL ENGINEERING

P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions

(2010) S. F. Maloney et al.   Integrative Biology

Grow with the flow: a spatial-temporal model of platelet deposition and blood coagulation under flow

(2010) K. Leiderman et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Threshold Response of Initiation of Blood Coagulation by Tissue Factor in Patterned Microfluidic Capillaries Is Controlled by Shear Rate

(2008) Feng Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates

(2008) K. B. NEEVES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS