Activation of transposable elements and genetic instability during long-term culture of the human fungal pathogen Candida albicans

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

FTIR and Raman Spectroscopy-Based Biochemical Profiling Reflects Genomic Diversity of Clinical Candida Isolates That May Be Useful for Diagnosis and Targeted Therapy of Candidiasis

(2019) Leszek Potocki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Senescence induction universally activates transposable element expression

(2018) Anthony R Colombo et al.   CELL CYCLE

Transposable element insertions in fission yeast drive adaptation to environmental stress

(2018) Caroline Esnault et al.   GENOME RESEARCH

A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans

(2017) Matthew Z. Anderson et al.   MICROBIOLOGY-SGM

Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host

(2017) Tejas Bouklas et al.   PLoS Pathogens

Tightening the connection between transposable element mobilization and aging

(2016) William C. Orr   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cell Wall Protein Ecm33 of Candida albicans is Involved in Chronological Life Span, Morphogenesis, Cell Wall Regeneration, Stress Tolerance, and Host–Cell Interaction

(2016) Ana Gil-Bona et al.   Frontiers in Microbiology

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

(2016) Marco De Cecco et al.   Aging-US

Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage

(2015) Maria E. Morales et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Effects of heat and UV radiation on the mobilization of transposon mariner-Mos1

(2015) Sinara Santos Jardim et al.   CELL STRESS & CHAPERONES

Affected chromosome homeostasis and genomic instability of clonal yeast cultures

(2015) Jagoda Adamczyk et al.   CURRENT GENETICS

Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability

(2015) Melissa N. Patterson et al.   DNA REPAIR

Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans

(2015) Meleah A. Hickman et al.   GENETICS

Trisomy of chromosome R confers resistance to triazoles in Candida albicans

(2015) Xingxing Li et al.   MEDICAL MYCOLOGY

The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival

(2015) Marcela Briones-Martin-del-Campo et al.   MICROBIOLOGY-SGM

Response of transposable elements to environmental stressors

(2015) Isabelle R. Miousse et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans

(2015) Meleah A. Hickman et al.   GENETICS

Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae

(2014) Anna Lewinska et al.   BIOGERONTOLOGY

Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging

(2014) Z. Hu et al.   GENES & DEVELOPMENT

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

(2014) Benjamin D. Harrison et al.   PLOS BIOLOGY

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

(2013) Marco De Cecco et al.   AGING CELL

Aging and cell death in the other yeasts,Schizosaccharomyces pombeandCandida albicans

(2013) Su-Ju Lin et al.   FEMS YEAST RESEARCH

Assessment of yeast chromosome XII instability: Single chromosome comet assay

(2013) Anna Lewinska et al.   FUNGAL GENETICS AND BIOLOGY

The ‘obligate diploid’ Candida albicans forms mating-competent haploids

(2013) Meleah A. Hickman et al.   NATURE

Human Transposon Tectonics

(2012) Kathleen H. Burns et al.   CELL

Replicative and Chronological Aging in Saccharomyces cerevisiae

(2012) Valter D. Longo et al.   Cell Metabolism

Caloric restriction restores the chronological life span of the goa1 null mutant of Candida albicans in spite of high cell levels of ROS

(2012) Hui Chen et al.   FUNGAL GENETICS AND BIOLOGY

The impact of transposable elements on eukaryotic genomes: From genome size increase to genetic adaptation to stressful environments

(2012) Benoît Chénais et al.   GENE

Transposon integration enhances expression of stress response genes

(2012) Gang Feng et al.   NUCLEIC ACIDS RESEARCH

A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast

(2011) Anna Lewinska et al.   BIOGERONTOLOGY

Enzymatic Dysfunction of Mitochondrial Complex I of the Candida albicansgoa1Mutant Is Associated with Increased Reactive Oxidants and Cell Death

(2011) Dongmei Li et al.   EUKARYOTIC CELL

Retrotransposition is associated with genome instability during chronological aging

(2011) P. H. Maxwell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular mechanism of chronological aging in yeast

(2010) Christopher R. Burtner et al.   CELL CYCLE

Genomic Plasticity of the Human Fungal Pathogen Candida albicans

(2010) Anna Selmecki et al.   EUKARYOTIC CELL

Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

RNAi in Budding Yeast

(2009) I. A. Drinnenberg et al.   SCIENCE

Candida albicans, a distinctive fungal model for cellular aging study

(2008) Xiao-Hong Fu et al.   AGING CELL

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

(2008) Anna Selmecki et al.   MOLECULAR MICROBIOLOGY