Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage

ERVK Polyprotein Processing and Reverse Transcriptase Expression in Human Cell Line Models of Neurological Disease

(2015) Mamneet Manghera et al.   Viruses-Basel

Evaluating the Extent of LINE-1 Mobility Following Exposure to Heavy Metals in HepG2 Cells

(2014) Abbas Karimi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

(2014) E. Helman et al.   GENOME RESEARCH

Widespread contribution of transposable elements to the innovation of gene regulatory networks

(2014) Vasavi Sundaram et al.   GENOME RESEARCH

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

(2014) Dawn deHaro et al.   NUCLEIC ACIDS RESEARCH

Exposure of hepatocellular carcinoma cells to low-level As2O3‎ causes an extra toxicity pathway via L1 retrotransposition ‎induction

(2014) Abbas Karimi et al.   TOXICOLOGY LETTERS

Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

(2013) Kathi Zarnack et al.   CELL

Retroelements in human disease

(2013) Kristel Kaer et al.   GENE

Mercury specifically induces LINE-1 activity in a human neuroblastoma cell line

(2013) Laleh Habibi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In Vitro Screening for Compounds That Enhance Human L1 Mobilization

(2013) Natsuko Terasaki et al.   PLoS One

Arsenic Induces VL30 Retrotransposition: The Involvement of Oxidative Stress and Heat-Shock Protein 70

(2013) Georgios Markopoulos et al.   TOXICOLOGICAL SCIENCES

Endogenous retroviruses: acquisition, amplification and taming of genome invaders

(2013) Marie Dewannieux et al.   Current Opinion in Virology

H2O2 signals via iron induction of VL30 retrotransposition correlated with cytotoxicity

(2012) Sofia Konisti et al.   FREE RADICAL BIOLOGY AND MEDICINE

The impact of transposable elements on eukaryotic genomes: From genome size increase to genetic adaptation to stressful environments

(2012) Benoît Chénais et al.   GENE

Exonization of transposed elements: A challenge and opportunity for evolution

(2011) Jürgen Schmitz et al.   BIOCHIMIE

Dynamic interactions between transposable elements and their hosts

(2011) Henry L. Levin et al.   NATURE REVIEWS GENETICS

The catalytic domain of all eukaryotic cut-and-paste transposase superfamilies

(2011) Y.-W. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons

(2010) Rebecca C. Iskow et al.   CELL

Genotoxicity of Soluble and Particulate Cadmium Compounds: Impact on Oxidative DNA Damage and Nucleotide Excision Repair

(2010) Tanja Schwerdtle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

What drives recombination hotspots to repeat DNA in humans?

(2010) G. McVean   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

All y’all need to know ‘bout retroelements in cancer

(2010) Victoria P. Belancio et al.   SEMINARS IN CANCER BIOLOGY

A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome

(2010) Miriam K. Konkel et al.   SEMINARS IN CANCER BIOLOGY

Repression of transposable-elements – a microRNA anti-cancer defense mechanism?

(2010) Reut Shalgi et al.   TRENDS IN GENETICS

Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination

(2010) Margaret L. Hoang et al.   PLoS Genetics

Mechanism of Cadmium-Mediated Inhibition of Msh2-Msh6 Function in DNA Mismatch Repair

(2009) Markus Wieland et al.   BIOCHEMISTRY

Alu repeats increase local recombination rates

(2009) David J Witherspoon et al.   BMC GENOMICS

Germline CDH1 deletions in hereditary diffuse gastric cancer families

(2009) C. Oliveira et al.   HUMAN MOLECULAR GENETICS

Alu-Alurecombination underlies the vast majority of largeVHLgermline deletions: Molecular characterization and genotype-phenotype correlations in VHL patients

(2009) Gerlind Franke et al.   HUMAN MUTATION

Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium

(2009) Adriana Arita et al.   Metallomics

The impact of retrotransposons on human genome evolution

(2009) Richard Cordaux et al.   NATURE REVIEWS GENETICS

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

(2008) Detmar Beyersmann et al.   ARCHIVES OF TOXICOLOGY

Endogenous retroviruses

(2008) I. A. Maksakova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ERCC1/XPF limits L1 retrotransposition

(2008) Stephen L. Gasior et al.   DNA REPAIR

Mammalian non-LTR retrotransposons: For better or worse, in sickness and in health

(2008) V. P. Belancio et al.   GENOME RESEARCH

Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway

(2008) Muriel Viau et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A universal classification of eukaryotic transposable elements implemented in Repbase

(2008) Vladimir V. Kapitonov et al.   NATURE REVIEWS GENETICS

Double-strand breaks associated with repetitive DNA can reshape the genome

(2008) J. L. Argueso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA