A Key Intermediate in Copper-Mediated Arene Trifluoromethylation, [n Bu4 N][Cu(Ar)(CF3 )3 ]: Synthesis, Characterization, and C(sp2 )−CF3 Reductive Elimination

Csp3–Csp3 Bond-Forming Reductive Elimination from Well-Defined Copper(III) Complexes

(2019) Matthew Paeth et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse copper(iii) trifluoromethyl complexes with mono-, bi- and tridentate ligands and their versatile reactivity

(2018) Song-Lin Zhang et al.   DALTON TRANSACTIONS

Organocopper(III) Compounds with Well-defined Structures Undergo Reductive Elimination to Form C-C or C-Heteroatom Bonds

(2018) Liang Liu et al.   CHINESE JOURNAL OF CHEMISTRY

Copper-Mediated 1,2-Bis(trifluoromethylation) of Arynes

(2018) Gavin Tsui et al.   Chemical Science

Organocopper(III) Spiro Complexes: Synthesis, Structural Characterization, and Redox Transformation

(2017) Liang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2017) Xinqiang Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Situ Generation of ArCu from CuF2 Makes Coupling of Bulky Aryl Silanes Feasible and Highly Efficient

(2016) Juan delPozo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ligand-dependent formation of ion-pair CuI/CuIII trifluoromethyl complexes containing bisphosphines

(2016) Song-Lin Zhang et al.   DALTON TRANSACTIONS

Isolation and characterization of copper(iii) trifluoromethyl complexes and reactivity studies of aerobic trifluoromethylation of arylboronic acids

(2016) Song-Lin Zhang et al.   RSC Advances

Easy Access to the Copper(III) Anion [Cu(CF3)4]−

(2015) Andrew M. Romine et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Oxidation of Ni(II) to Ni(IV) with Aryl Electrophiles Enables Ni-Mediated Aryl–CF3 Coupling

(2015) James R. Bour et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Trifluoromethylation of Aryl- and Vinylboronic Acids by 2-Cyclopropyl-1-(trifluoromethyl)benzo[b]thiophenium Triflate

(2015) Sadayuki Arimori et al.   ORGANIC LETTERS

Computational Ligand Design for the Reductive Elimination of ArCF3from a Small Bite Angle PdIIComplex: Remarkable Effect of a Perfluoroalkyl Phosphine

(2014) Mads C. Nielsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Synthesis of High-Valent Aryl–Cu(II) and Aryl–Cu(III) Compounds: Mechanistic Insight into Arene C–H Bond Metalation

(2014) Hu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Trifluoromethylation of Aryl Halides with CuCF3 and the Ortho Effect

(2014) Andrey I. Konovalov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Trifluoromethylation of Aryl and Heteroaryl Halides with Fluoroform-Derived CuCF3: Scope, Limitations, and Mechanistic Features

(2013) Anton Lishchynskyi et al.   JOURNAL OF ORGANIC CHEMISTRY

The role of organometallic copper(iii) complexes in homogeneous catalysis

(2013) Alicia Casitas et al.   Chemical Science

Fluoroform-Derived CuCF3for Low-Cost, Simple, Efficient, and Safe Trifluoromethylation of Aryl Boronic Acids in Air

(2012) Petr Novák et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Trifluoromethylation of Arylboronates with Shelf-Stable Potassium (Trifluoromethyl)trimethoxyborate

(2012) Bilal A. Khan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Developments on the Trifluoromethylation of (Hetero)Arenes

(2012) Xiao-Feng Wu et al.   Chemistry-An Asian Journal

Progress in Copper-Mediated Formation of Trifluoromethylated Arenes

(2012) Tianfei Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Merging Visible-Light Photocatalysis and Transition-Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I

(2012) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-valent organometallic copper and palladium in catalysis

(2012) Amanda J. Hickman et al.   NATURE

Hydrophobically Assisted Separation-Friendly Mitsunobu Reaction

(2012) Xin-Shan Ye et al.   SYNLETT

A General Strategy for the Perfluoroalkylation of Arenes and Arylbromides by Using Arylboronate Esters and [(phen)CuRF]

(2011) Nichole D. Litvinas et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Broadly Applicable Copper Reagent for Trifluoromethylations and Perfluoroalkylations of Aryl Iodides and Bromides

(2011) Hiroyuki Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-mediated trifluoromethylation of arylboronic acids by trifluoromethyl sulfonium salts

(2011) Cheng-Pan Zhang et al.   CHEMICAL COMMUNICATIONS

Copper-catalyzed trifluoromethylation of aryl boronic acids using a CF3+ reagent

(2011) Jun Xu et al.   CHEMICAL COMMUNICATIONS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Mechanisms of Nucleophilic Organocopper(I) Reactions

(2011) Naohiko Yoshikai et al.   CHEMICAL REVIEWS

Observation and Mechanistic Study of Facile CO Bond Formation between a Well-Defined Aryl-Copper(III) Complex and Oxygen Nucleophiles

(2011) Lauren M. Huffman et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Room Temperature Aryl Trifluoromethylation via Copper-Mediated Oxidative Cross-Coupling

(2011) Todd D. Senecal et al.   JOURNAL OF ORGANIC CHEMISTRY

Nucleophilic Aryl Fluorination and Aryl Halide Exchange Mediated by a CuI/CuIIICatalytic Cycle

(2011) Alicia Casitas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

(2011) Tianfei Liu et al.   ORGANIC LETTERS

Trifluoromethylation of aryl and heteroaryl halides

(2011) Sudipta Roy et al.   TETRAHEDRON

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Aryl−CF3Bond-Forming Reductive Elimination from Palladium(IV)

(2010) Nicholas D. Ball et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids

(2010) Lingling Chu et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

Direct observation of CuI/CuIII redox steps relevant to Ullmann-type coupling reactions

(2010) Alicia Casitas et al.   Chemical Science

Aromatic trifluoromethylation catalytic in copper

(2009) Masahiro Oishi et al.   CHEMICAL COMMUNICATIONS

Room-temperature aerobic formation of a stable aryl–Cu(iii) complex and its reactions with nucleophiles: highly efficient and diverse arene C–H functionalizations of azacalix[1]arene[3]pyridine

(2009) Bo Yao et al.   CHEMICAL COMMUNICATIONS

Fluorine in medicinal chemistry: a century of progress and a 60-year retrospective of selected highlights

(2009) Robert Filler et al.   Future Medicinal Chemistry

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Preparation of σ- and π-Allylcopper(III) Intermediates in SN2 and SN2′ Reactions of Organocuprate(I) Reagents with Allylic Substrates

(2008) Erika R. Bartholomew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Active Trifluoromethylating Agents from Well-Defined Copper(I)−CF3Complexes

(2008) Galyna G. Dubinina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbon−Nitrogen Bond Formation Involving Well-Defined Aryl−Copper(III) Complexes

(2008) Lauren M. Huffman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS