The Concentration of Plasma Provides Additional Bioactive Proteins in Platelet and Autologous Protein Solutions

Human blood-based anti-inflammatory solution inhibits osteoarthritis progression in a meniscal-tear rat study

(2017) William King et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Intra-articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis

(2017) Himanshu Bansal et al.   Journal of Translational Medicine

The effects of different doses of IGF-1 on cartilage and subchondral bone during the repair of full-thickness articular cartilage defects in rabbits

(2017) Z. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

TGF-β Family Signaling in Mesenchymal Differentiation

(2017) Ingo Grafe et al.   Cold Spring Harbor Perspectives in Biology

Short-term clinical results of intra-articular PRP injections for early osteoarthritis of the knee

(2017) Po-Hua Huang et al.   International Journal of Surgery

Platelet-Rich Plasma for the Management of Hip and Knee Osteoarthritis

(2017) Kim L. Bennell et al.   Current Rheumatology Reports

IGF-1 Gene Transfer to Human Synovial MSCs Promotes Their Chondrogenic Differentiation Potential without Induction of the Hypertrophic Phenotype

(2017) Yasutoshi Ikeda et al.   Stem Cells International

Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β–Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte

(2016) Mohammad Shahidul Makki et al.   AMERICAN JOURNAL OF PATHOLOGY

Hyaluronic Acid Versus Platelet-Rich Plasma: A Prospective, Double-Blind Randomized Controlled Trial Comparing Clinical Outcomes and Effects on Intra-articular Biology for the Treatment of Knee Osteoarthritis

(2016) Brian J. Cole et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Comparison of humoral insulin-like growth factor-1, platelet-derived growth factor-BB, transforming growth factor-β1, and interleukin-1 receptor antagonist concentrations among equine autologous blood-derived preparations

(2016) Christiane R. Ionita et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Leukocyte-poor platelet-rich plasma is more effective than the conventional therapy with acetaminophen for the treatment of early knee osteoarthritis

(2016) Mario Simental-Mendía et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Influence of IGF1, TGFβ1, bFGF and G-CSF/M-CSF on the mRNA levels of selected matrix proteins, cytokines, metalloproteinase 3 and TIMP1 in rat synovial membrane cells

(2016) Anna Osiecka-Iwan et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

IGF-I induces adipose derived mesenchymal cell chondrogenic differentiation in vitro and enhances chondrogenesis in vivo

(2016) Quan Zhou et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis

(2016) Jinjiang Yang et al.   Molecular Medicine Reports

Adeno-associated virus gene therapy vector scAAVIGF-I for transduction of equine articular chondrocytes and RNA-seq analysis

(2016) D.D. Hemphill et al.   OSTEOARTHRITIS AND CARTILAGE

Influence of Interleukin-1 Beta on Platelet-Poor Plasma Clot Formation: A Potential Impact on Early Bone Healing

(2016) Xin Wang et al.   PLoS One

Evaluation of a Single Intra-Articular Injection of Autologous Protein Solution for Treatment of Osteoarthritis in a Canine Population

(2016) Audrey W. Wanstrath et al.   VETERINARY SURGERY

Leukocyte-Reduced Platelet-Rich Plasma Normalizes Matrix Metabolism in Torn Human Rotator Cuff Tendons

(2015) Jessica A. Cross et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Does intraoperative application of leukocyte-poor platelet-rich plasma during arthroscopy for knee degeneration affect postoperative pain, function and quality of life? A 12-month randomized controlled double-blind trial

(2015) Christian Duif et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Positive impact of IGF-1-coupled nanoparticles on the differentiation potential of human chondrocytes cultured on collagen scaffolds

(2015) Juliane Pasold et al.   International Journal of Nanomedicine

­­­­­Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis

(2015) Tomoya Uchimura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Implantation of rAAV5-IGF-I Transduced Autologous Chondrocytes Improves Cartilage Repair in Full-thickness Defects in the Equine Model

(2015) Kyla F Ortved et al.   MOLECULAR THERAPY

Autologous-Conditioned Serum: Evidence for Use in the Knee

(2015) David Frisbie   Journal of Knee Surgery

Evaluation of a single intra-articular injection of autologous protein solution for treatment of osteoarthritis in horses

(2014) Alicia L. Bertone et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

(2014) M Cucchiarini et al.   GENE THERAPY

Autologous protein solution prepared from the blood of osteoarthritic patients contains an enhanced profile of anti-inflammatory cytokines and anabolic growth factors

(2014) Krista O'Shaughnessey et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Anti-inflammatory and Matrix Restorative Mechanisms of Platelet-Rich Plasma in Osteoarthritis

(2013) Emily A. Sundman et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Autologous solution protects bovine cartilage explants from IL-1α- and TNFα-induced cartilage degradation

(2013) Andrea Matuska et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Intra-Articular Use of a Platelet-Rich Product in Normal Horses: Clinical Signs and Cytologic Responses

(2013) Jamie A. Textor et al.   VETERINARY SURGERY

Genetic Engineering of Juvenile Human Chondrocytes Improves Scaffold-free Mosaic Neocartilage Grafts

(2012) Vincent Y. Ng et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Effects of Platelet-Rich Plasma Composition on Anabolic and Catabolic Activities in Equine Cartilage and Meniscal Explants

(2012) John D. Kisiday et al.   Cartilage

Autologous protein solution inhibits MMP-13 production by IL-1β and TNFα-stimulated human articular chondrocytes

(2011) Jennifer Woodell-May et al.   JOURNAL OF ORTHOPAEDIC RESEARCH