Overexpression of human IGF-I via direct rAAV-mediated gene transfer improves the early repair of articular cartilage defects in vivo

Combined Effects of Connective Tissue Growth Factor-Modified Bone Marrow-Derived Mesenchymal Stem Cells and NaOH-Treated PLGA Scaffolds on the Repair of Articular Cartilage Defect in Rabbits

(2014) Songsong Zhu et al.   CELL TRANSPLANTATION

Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model

(2013) Kyobum Kim et al.   JOURNAL OF CONTROLLED RELEASE

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

(2013) Jagadeesh K Venkatesan et al.   Journal of Translational Medicine

Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes

(2012) Emmanuelle Renard et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Direct rAAV SOX9 administration for durable articular cartilage repair with delayed terminal differentiation and hypertrophy in vivo

(2012) Magali Cucchiarini et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Reconstruct large osteochondral defects of the knee with hIGF-1 gene enhanced Mosaicplasty

(2012) Ping Leng et al.   KNEE

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(2012) Anja Weimer et al.   MOLECULAR MEDICINE

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

(2012) Jagadeesh K Venkatesan et al.   Stem Cell Research & Therapy

Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair

(2011) Tong Ming Liu et al.   ARTHRITIS AND RHEUMATISM

Chondromodulin 1 stabilizes the chondrocyte phenotype and inhibits endochondral ossification of porcine cartilage repair tissue

(2011) Patricia Klinger et al.   ARTHRITIS AND RHEUMATISM

The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells

(2011) Lei Cao et al.   BIOMATERIALS

SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat

(2011) Jong-Min Lee et al.   BIOMATERIALS

Direct delayed human adenoviral BMP-2 or BMP-6 gene therapy for bone and cartilage regeneration in a pony osteochondral model

(2011) M.I. Menendez et al.   OSTEOARTHRITIS AND CARTILAGE

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway

(2011) Azadeh Montaseri et al.   PLoS One

Metabolic Activities and Chondrogenic Differentiation of Human Mesenchymal Stem Cells Following Recombinant Adeno-Associated Virus–Mediated Gene Transfer and Overexpression of Fibroblast Growth Factor 2

(2011) Magali Cucchiarini et al.   TISSUE ENGINEERING PART A

Articular cartilage repair by genetically modified bone marrow aspirate in sheep

(2010) A Ivkovic et al.   GENE THERAPY

The influence of the stable expression of BMP2 in fibrin clots on the remodelling and repair of osteochondral defects

(2009) Stephan Vogt et al.   BIOMATERIALS

Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined withSox9 viarAAV gene transfer

(2008) Magali Cucchiarini et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells

(2007) Lorenz Uebersax et al.   JOURNAL OF CONTROLLED RELEASE