Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells

Bevacizumab may improve quality of life, but not overall survival in glioblastoma: an epidemiological study

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Girdin protein: A potential metastasis predictor associated with prognosis in lung cancer

(2018) Zhaoyang Yang et al.   Experimental and Therapeutic Medicine

The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment

(2017) Nakho Chang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Girdin protein expression is associated with poor prognosis in patients with invasive breast cancer

(2017) Jong-Sun Choi et al.   PATHOLOGY

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine

(2017) Katharina J. Wenger et al.   Oncology Letters

Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5

(2017) Yali Chen et al.   Oncotarget

The Role of Hypoxia in Glioblastoma Invasion

(2017) Ana Monteiro et al.   Cells

The PI3K/AKT Pathway as a Target for Cancer Treatment

(2016) Ingrid A. Mayer et al.   Annual Review of Medicine

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013

(2016) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Single cell rigidity sensing: A complex relationship between focal adhesion dynamics and large-scale actin cytoskeleton remodeling

(2016) Mukund Gupta et al.   Cell Adhesion & Migration

Stellettin B Induces G1 Arrest, Apoptosis and Autophagy in Human Non-small Cell Lung Cancer A549 Cells via Blocking PI3K/Akt/mTOR Pathway

(2016) Ran Wang et al.   Scientific Reports

Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

(2015) Kimmo J. Hatanpaa et al.   NEOPLASIA

Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells

(2014) Feng Gu et al.   JOURNAL OF NEUROCHEMISTRY

In Vitro Antitumor Activity of Stellettin B, a Triterpene from Marine Sponge Jaspis stellifera, on Human Glioblastoma Cancer SF295 Cells

(2014) Sheng-An Tang et al.   Marine Drugs

Targeting adaptive glioblastoma: an overview of proliferation and invasion

(2014) Q. Xie et al.   NEURO-ONCOLOGY

Actin Filaments at the Leading Edge of Cancer Cells Are Characterized by a High Mobile Fraction and Turnover Regulation by Profilin I

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EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

(2013) Krishna M. Talasila et al.   ACTA NEUROPATHOLOGICA

The role of Stat3 in glioblastoma multiforme

(2013) Rodney B. Luwor et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial

(2013) Mark R. Gilbert et al.   JOURNAL OF CLINICAL ONCOLOGY

Using the molecular classification of glioblastoma to inform personalized treatment

(2013) Adriana Olar et al.   JOURNAL OF PATHOLOGY

Angiogenesis in Glioblastoma

(2013) Sunit Das et al.   NEW ENGLAND JOURNAL OF MEDICINE

Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR

(2012) Daniela Coltrini et al.   ANGIOGENESIS

Targeting the EGFR signaling pathway in cancer therapy

(2012) Parthasarathy Seshacharyulu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

STAT3 Protein Up-regulates Gα-interacting Vesicle-associated Protein (GIV)/Girdin Expression, and GIV Enhances STAT3 Activation in a Positive Feedback Loop during Wound Healing and Tumor Invasion/Metastasis

(2012) Ying Dunkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era

(2012) Christine Carico et al.   PLoS One

Angiogenesis and invasion in glioma

(2011) Manabu Onishi et al.   Brain Tumor Pathology

Targeting the AKT Pathway in Glioblastoma

(2011) Kelli A. McDowell et al.   CURRENT PHARMACEUTICAL DESIGN

Girdin Is an Intrinsic Regulator of Neuroblast Chain Migration in the Rostral Migratory Stream of the Postnatal Brain

(2011) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Girdin maintains the stemness of glioblastoma stem cells

(2011) A Natsume et al.   ONCOGENE

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocrine regulation of glioblastoma cell-cycle progression, viability and radioresistance through the VEGF-VEGFR2 (KDR) interplay

(2010) Petra Knizetova et al.   CELL CYCLE

Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer

(2010) Mikel Garcia-Marcos et al.   FASEB JOURNAL

Activated STAT3 Regulates Hypoxia-Induced Angiogenesis and Cell Migration in Human Glioblastoma

(2010) Shin-Hyuk Kang et al.   NEUROSURGERY

Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting

(2009) Amina A Qutub et al.   BMC Systems Biology

Brain angiogenesis in developmental and pathological processes: mechanism and therapeutic intervention in brain tumors

(2009) Woo-Young Kim et al.   FEBS Journal

An Actin-Binding Protein Girdin Regulates the Motility of Breast Cancer Cells

(2008) P. Jiang et al.   CANCER RESEARCH

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer

(2008) Y. Rebecca Chin et al.   CELLULAR SIGNALLING

AKT Signaling in Regulating Angiogenesis

(2008) Bing-Hua Jiang et al.   CURRENT CANCER DRUG TARGETS

Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin

(2008) Tomoya Kitamura et al.   NATURE CELL BIOLOGY