Tau exhibits unique seeding properties in globular glial tauopathy

Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies

(2018) Chao Peng et al.   NATURE

Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy

(2018) Sonia Lorena Espíndola et al.   Cell Reports

Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease

(2018) Lingyan Ping et al.   Scientific Data

Structures of filaments from Pick’s disease reveal a novel tau protein fold

(2018) Benjamin Falcon et al.   NATURE

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

(2018) Tritia R. Yamasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

(2018) Erik C. B. Johnson et al.   Molecular Neurodegeneration

Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies

(2017) Kevin H. Strang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An acetylation–phosphorylation switch that regulates tau aggregation propensity and function

(2017) Yari Carlomagno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

(2017) Sneha Narasimhan et al.   JOURNAL OF NEUROSCIENCE

Glial contributions to neurodegeneration in tauopathies

(2017) Cheryl E. G. Leyns et al.   Molecular Neurodegeneration

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

Distinct phenotypes of three-repeat and four-repeat human tau in a transgenic model of tauopathy

(2017) Megan A. Sealey et al.   NEUROBIOLOGY OF DISEASE

Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice

(2016) Jing L. Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Shared and Distinct Patterns of Oligodendroglial Response in α-Synucleinopathies and Tauopathies

(2016) Zdenek Rohan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons

(2016) Sofia Söllvander et al.   Molecular Neurodegeneration

Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model

(2016) Kathleen M. Schoch et al.   NEURON

Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo

(2016) Sarah K. Kaufman et al.   NEURON

Characterizing Protein–Protein Interactions Using Mass Spectrometry: Challenges and Opportunities

(2016) Arne H. Smits et al.   TRENDS IN BIOTECHNOLOGY

A novel tau mutation, p.K317N, causes globular glial tauopathy

(2015) Pawel Tacik et al.   ACTA NEUROPATHOLOGICA

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

(2015) Casey Cook et al.   HUMAN MOLECULAR GENETICS

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Invited review: Neuropathology of tauopathies: principles and practice

(2015) G. G. Kovacs   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Multiple-System Atrophy

(2015) Alessandra Fanciulli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

(2014) Benjamin Falcon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Astrocytic inclusions in progressive supranuclear palsy and corticobasal degeneration

(2014) Mari Yoshida   NEUROPATHOLOGY

Proteopathic tau seeding predicts tauopathy in vivo

(2014) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Globular glial tauopathies (GGT): consensus recommendations

(2013) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

Glial and Neuronal Tau Pathology in Tauopathies

(2013) Isidre Ferrer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies

(2011) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

(2010) Stephanie J. Adams et al.   PLoS One