Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling

Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections

(2017) Benson Ogunjimi et al.   JOURNAL OF CLINICAL INVESTIGATION

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes

(2017) Silvia Cerboni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death

(2017) Bridget Larkin et al.   JOURNAL OF IMMUNOLOGY

Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

(2017) Liliane Christ et al.   TRENDS IN BIOCHEMICAL SCIENCES

Signalling strength determines proapoptotic functions of STING

(2017) Muhammet F. Gulen et al.   Nature Communications

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

(2016) Christian K. Holm et al.   Nature Communications

Viruses transfer the antiviral second messenger cGAMP between cells

(2015) A. Bridgeman et al.   SCIENCE

Transmission of innate immune signaling by packaging of cGAMP in viral particles

(2015) Matteo Gentili et al.   SCIENCE

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

(2015) S. Liu et al.   SCIENCE

Listeria monocytogenes induces IFN  expression through an IFI16-, cGAS- and STING-dependent pathway

(2014) K. Hansen et al.   EMBO JOURNAL

Exosomes and other extracellular vesicles in host-pathogen interactions

(2014) J. S. Schorey et al.   EMBO REPORTS

Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

(2014) Mark A. Czuczman et al.   NATURE

T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses: Implications for Restriction of HIV Replication

(2014) Randi K. Berg et al.   PLoS One

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors

(2013) K. A. Horan et al.   JOURNAL OF IMMUNOLOGY

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

(2013) Andrea Ablasser et al.   NATURE

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

RIG-I detects infection with liveListeriaby sensing secreted bacterial nucleic acids

(2012) Zeinab Abdullah et al.   EMBO JOURNAL

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

STING is a direct innate immune sensor of cyclic di-GMP

(2011) Dara L. Burdette et al.   NATURE

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

(2010) Sarah Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type I IFN Signaling Constrains IL-17A/F Secretion by    T Cells during Bacterial Infections

(2010) T. Henry et al.   JOURNAL OF IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes

(2009) Silvia Stockinger et al.   PLoS Pathogens

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE