T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses: Implications for Restriction of HIV Replication

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Innate immunity in the control of HIV/AIDS

(2012) Mickaël J.-Y. Ploquin et al.   AIDS

The evolving epidemiology of HIV/AIDS

(2012) Kevin M. De Cock et al.   AIDS

IFN-α and TRAIL: A double edge sword in HIV-1 disease?

(2012) Marie-Lise Gougeon et al.   EXPERIMENTAL CELL RESEARCH

Innate Immune Recognition of HIV-1

(2012) Akiko Iwasaki   IMMUNITY

Plasmacytoid Dendritic Cells (pDCs) From HIV Controllers Produce Interferon-α and Differentiate Into Functional Killer pDCs Under HIV Activation

(2012) Lucie Barblu et al.   JOURNAL OF INFECTIOUS DISEASES

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

(2012) Manqing Li et al.   NATURE

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

(2012) Hanna-Mari Baldauf et al.   NATURE MEDICINE

Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA

(2012) Randi K. Berg et al.   PLoS One

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Regulation of Mycobacterium tuberculosis-Dependent HIV-1 Transcription Reveals a New Role for NFAT5 in the Toll-Like Receptor Pathway

(2012) Shahin Ranjbar et al.   PLoS Pathogens

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

(2012) Brian J Ferguson et al.   eLife

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Innate Sensing of HIV-Infected Cells

(2011) Alice Lepelley et al.   PLoS Pathogens

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Neisseria gonorrhoeae effectively blocks HIV-1 replication by eliciting a potent TLR9-dependent interferon-α response from plasmacytoid dendritic cells

(2010) Wendy N. Dobson-Belaire et al.   CELLULAR MICROBIOLOGY

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

(2010) M. Solis et al.   JOURNAL OF VIROLOGY

DNA-dependent activator of IFN-regulatory factors enhances the transcription of HIV-1 through NF-κB

(2010) Takaya Hayashi et al.   MICROBES AND INFECTION

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

(2010) Nan Yan et al.   NATURE IMMUNOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Contrasting Roles for TLR Ligands in HIV-1 Pathogenesis

(2010) Beda Brichacek et al.   PLoS One

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton

(2010) P. U. Cameron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune recognition and activation during HIV infection

(2010) Trine H Mogensen et al.   Retrovirology

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

(2010) Jasminka Sterjovski et al.   VIROLOGY

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells

(2009) C. K. Holm et al.   JOURNAL OF IMMUNOLOGY

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

(2009) B. P. Doehle et al.   JOURNAL OF VIROLOGY

Partial Inhibition of Human Immunodeficiency Virus Replication by Type I Interferons: Impact of Cell-to-Cell Viral Transfer

(2009) D. Vendrame et al.   JOURNAL OF VIROLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1

(2009) Angela Meier et al.   NATURE MEDICINE

Cell Biology of HIV-1 Infection of Macrophages

(2008) Carol A. Carter et al.   Annual Review of Microbiology

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE

Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis

(2008) Nicholas Funderburg et al.   PLoS One