Identification of antiviral roles for the exon–junction complex and nonsense-mediated decay in flaviviral infection

Rewiring cellular networks by members of the Flaviviridae family

(2018) Christopher J. Neufeldt et al.   NATURE REVIEWS MICROBIOLOGY

Zika virus–related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice

(2018) Derek J. Platt et al.   Science Translational Medicine

Anticipating Emerging Mosquito-borne Flaviviruses in the USA: What Comes after Zika?

(2018) Michelle V. Evans et al.   TRENDS IN PARASITOLOGY

A Global Interactome Map of the Dengue Virus NS1 Identifies Virus Restriction and Dependency Host Factors

(2018) Mohamed Lamine Hafirassou et al.   Cell Reports

ICE1 promotes the link between splicing and nonsense-mediated mRNA decay

(2018) Thomas D Baird et al.   eLife

Global interactomics uncovers extensive organellar targeting by Zika virus

(2018) Etienne Coyaud et al.   MOLECULAR & CELLULAR PROTEOMICS

An orthogonal proteomic survey uncovers novel Zika virus host factors

(2018) Pietro Scaturro et al.   NATURE

A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication

(2018) R. Blake Richardson et al.   Nature Microbiology

CORUM: the comprehensive resource of mammalian protein complexes—2019

(2018) Madalina Giurgiu et al.   NUCLEIC ACIDS RESEARCH

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

(2018) Krystal A. Fontaine et al.   mBio

The IMPORTance of the Nucleus during Flavivirus Replication

(2017) Adam Lopez-Denman et al.   Viruses-Basel

Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex

(2017) David L. Lin et al.   mBio

Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus

(2017) Keiko Rausch et al.   Cell Reports

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

(2016) Jonathan J. Miner et al.   CELL

Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses

(2016) Laurent Chatel-Chaix et al.   Cell Host & Microbe

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

(2016) Nicholas S. Heaton et al.   IMMUNITY

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

Mechanism and regulation of the nonsense-mediated decay pathway

(2016) Nele Hug et al.   NUCLEIC ACIDS RESEARCH

The eIF4AIII RNA helicase is a critical determinant of human cytomegalovirus replication

(2016) Ben Ziehr et al.   VIROLOGY

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly

(2016) Hanqian Mao et al.   PLoS Genetics

The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

(2016) Federico A. De Maio et al.   PLoS Pathogens

Rbm8a Haploinsufficiency Disrupts Embryonic Cortical Development Resulting in Microcephaly

(2015) H. Mao et al.   JOURNAL OF NEUROSCIENCE

A Combined Proteomics/Genomics Approach Links Hepatitis C Virus Infection with Nonsense-Mediated mRNA Decay

(2015) Holly R. Ramage et al.   MOLECULAR CELL

Global Mapping of Herpesvirus-Host Protein Complexes Reveals a Transcription Strategy for Late Genes

(2015) Zoe H. Davis et al.   MOLECULAR CELL

Identification of elements in human long 3′ UTRs that inhibit nonsense-mediated decay

(2015) Kalodiah G. Toma et al.   RNA

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

(2015) Hongming Ma et al.   Cell Reports

Nonsense-Mediated Decay Serves as a General Viral Restriction Mechanism in Plants

(2014) Damien Garcia et al.   Cell Host & Microbe

The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication

(2014) Giuseppe Balistreri et al.   Cell Host & Microbe

Genome-Wide RNAi Screen Identifies Broadly-Acting Host Factors That Inhibit Arbovirus Infection

(2014) Ari Yasunaga et al.   PLoS Pathogens

Nucleolin Interacts with the Dengue Virus Capsid Protein and Plays a Role in Formation of Infectious Virus Particles

(2013) C. A. Balinsky et al.   JOURNAL OF VIROLOGY

UPF1 Is Crucial for the Infectivity of Human Immunodeficiency Virus Type 1 Progeny Virions

(2013) A. K. P. Serquina et al.   JOURNAL OF VIROLOGY

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay

(2013) Kusum K Singh et al.   RNA Biology

Adaptor protein complexes-1 and 3 are involved at distinct stages of flavivirus life-cycle

(2013) Tanvi Agrawal et al.   Scientific Reports

The Human T-Lymphotropic Virus Type 1 Tax Protein Inhibits Nonsense-Mediated mRNA Decay by Interacting with INT6/EIF3E and UPF1

(2012) V. Mocquet et al.   JOURNAL OF VIROLOGY

Global landscape of HIV–human protein complexes

(2011) Stefanie Jäger et al.   NATURE

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

(2011) Stefanie Jäger et al.   NATURE

A public genome-scale lentiviral expression library of human ORFs

(2011) Xiaoping Yang et al.   NATURE METHODS

Dengue Virus Capsid Protein Binds Core Histones and Inhibits Nucleosome Formation in Human Liver Cells

(2011) Tonya M. Colpitts et al.   PLoS One

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs

(2010) James R Boyne et al.   EMBO JOURNAL

The exon junction complex component Magoh controls brain size by regulating neural stem cell division

(2010) Debra L Silver et al.   NATURE NEUROSCIENCE

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

Disassembly of Exon Junction Complexes by PYM

(2009) Niels H. Gehring et al.   CELL

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay

(2009) Niels H. Gehring et al.   PLOS BIOLOGY

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE