Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats

Elevated cannabinoid receptor 1 and G protein-coupled receptor 55 expression in proximal tubule cells and whole kidney exposed to diabetic conditions

(2015) Kayte A Jenkin et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

γ-Secretase inhibition promotes fibrotic effects of albumin in proximal tubular epithelial cells

(2013) C Slattery et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid Receptor 2 Expression in Human Proximal Tubule Cells is Regulated by Albumin Independent of ERK1/2 Signaling

(2013) Kayte A. Jenkin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

CB1receptor signaling regulates social anxiety and memory

(2013) Y. Litvin et al.   GENES BRAIN AND BEHAVIOR

Kidney Disease and Increased Mortality Risk in Type 2 Diabetes

(2013) M. Afkarian et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats

(2013) Ikram Merroun et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Lipid mediators of inflammation in obesity-related glomerulopathy

(2013) E. Nolan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

(2012) Joseph Tam et al.   Cell Metabolism

Na+-H+ Exchanger Regulatory Factor 1 (NHERF1) PDZ Scaffold Binds an Internal Binding Site in the Scavenger Receptor Megalin

(2012) Craig Slattery et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Blockade of Cannabinoid Receptor 1 Improves Insulin Resistance, Lipid Metabolism, and Diabetic Nephropathy in db/db Mice

(2012) D. H. Nam et al.   ENDOCRINOLOGY

The interaction between megalin and ClC-5 is scaffolded by the Na+–H+ exchanger regulatory factor 2 (NHERF2) in proximal tubule cells

(2012) D.H. Hryciw et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Endocannabinoids and the renal proximal tubule: An emerging role in diabetic nephropathy

(2012) Kayte A. Jenkin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role for Cannabinoid Receptors in Human Proximal Tubular Hypertrophy

(2011) Kayte A. Jenkin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis

(2011) Xuan Xia et al.   PLoS One

GPR55 ligands promote receptor coupling to multiple signalling pathways

(2010) Christopher M Henstridge et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy

(2010) F. Barutta et al.   DIABETES

Cannabinoid receptor 1 mediates palmitic acid-induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells

(2010) J.C. Lim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice

(2009) A. K. H. Lim et al.   DIABETOLOGIA

Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control

(2009) M-H Son et al.   INTERNATIONAL JOURNAL OF OBESITY

Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands

(2009) Ankur Kapur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding

(2009) M K Judge et al.   JOURNAL OF ENDOCRINOLOGY

Variation of serum creatinine, cystatin C, and creatinine clearance tests in persons with normal renal function

(2008) John G. Toffaletti et al.   CLINICA CHIMICA ACTA

SERENADE: The Study Evaluating Rimonabant Efficacy in Drug-Naive Diabetic Patients: Effects of monotherapy with rimonabant, the first selective CB1 receptor antagonist, on glycemic control, body weight, and lipid profile in drug-naive type 2 diabetes

(2008) J. Rosenstock et al.   DIABETES CARE

The endocannabinoid system in obesity and type 2 diabetes

(2008) V. Di Marzo   DIABETOLOGIA

Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease

(2008) Julie A. Jonassen et al.   JOURNAL OF CELL BIOLOGY

Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance

(2008) A. P. Jayasooriya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY

Association between obesity and kidney disease: A systematic review and meta-analysis

(2007) Y. Wang et al.   KIDNEY INTERNATIONAL