Gap junctions and connexins as therapeutic targets in cancer

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Combinational treatment of gap junctional activator and tamoxifen in breast cancer cells

(2009) Gunjan Gakhar et al.   ANTI-CANCER DRUGS

Mitochondrial apoptosis is amplified through gap junctions

(2009) Pablo M. Peixoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Connexin43 phosphorylation: structural changes and biological effects

(2009) Joell L. Solan et al.   BIOCHEMICAL JOURNAL

The anti-glioma effect of suicide gene therapy using BMSC expressing HSV/TK combined with overexpression of Cx43 in glioma cells

(2009) Q Huang et al.   CANCER GENE THERAPY

HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells

(2009) Miroslava Matuskova et al.   CANCER LETTERS

Overexpression of Protease-Activated Receptor-1 Contributes to Melanoma Metastasis via Regulation of Connexin 43

(2009) G. J. Villares et al.   CANCER RESEARCH

Src-Induced Cisplatin Resistance Mediated by Cell-to-Cell Communication

(2009) E. Peterson-Roth et al.   CANCER RESEARCH

Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis

(2009) Tao Huang et al.   CANCER SCIENCE

Connexins: a myriad of functions extending beyond assembly of gap junction channels

(2009) Hashem A Dbouk et al.   Cell Communication and Signaling

The role of the cytoskeleton in the formation of gap junctions by Connexin 30

(2009) Chunyan Qu et al.   EXPERIMENTAL CELL RESEARCH

Gap Junction Communication between Autologous Endothelial and Tumor Cells Induce Cross-Recognition and Elimination by Specific CTL

(2009) H. Benlalam et al.   JOURNAL OF IMMUNOLOGY

Direct Antigen Presentation and Gap Junction Mediated Cross-Presentation during Apoptosis

(2009) B. Pang et al.   JOURNAL OF IMMUNOLOGY

Enhanced Effect of Connexin 43 on Cisplatin-Induced Cytotoxicity in Mesothelioma Cells

(2009) Hiromi Sato et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Connexin43 pseudogene in breast cancer cells offers a novel therapeutic target

(2009) A. Bier et al.   MOLECULAR CANCER THERAPEUTICS

A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer

(2009) M. Trepel et al.   MOLECULAR CANCER THERAPEUTICS

Connexin 33 Impairs Gap Junction Functionality by Accelerating Connexin 43 Gap Junction Plaque Endocytosis

(2009) Diane Carette et al.   TRAFFIC

Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium

(2008) M Khair Elzarrad et al.   BMC Medicine

5-Aza-2′-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene

(2008) H Hagiwara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model

(2008) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Alterations in Cx43 and OB-cadherin affect breast cancer cell metastatic potential

(2008) Zhongyong Li et al.   CLINICAL & EXPERIMENTAL METASTASIS

Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs

(2008) Zhongyong Li et al.   CLINICAL & EXPERIMENTAL METASTASIS

Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells

(2008) M A Westhoff et al.   ONCOGENE