PLD3 Rare Variants Identified in Late-Onset Alzheimer’s Disease Affect Amyloid-β Levels in Cellular Model

Impact of late-onset Alzheimer’s genetic risk factors on beta-amyloid endocytic production

(2018) Cláudia Guimas Almeida et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing

(2018) Aamir S. Mukadam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rare Variants in PLD3 Increase Risk for Alzheimer’s Disease in Han Chinese

(2018) Meng-Shan Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention

(2018) Corinne D. Engelman et al.   NEUROBIOLOGY OF AGING

PLD3 gene and processing of APP

(2017) Pietro Fazzari et al.   NATURE

Association and interaction effects of Alzheimer’s disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population

(2017) Eugene Lin et al.   Oncotarget

Rare Variants inPLD3Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

(2015) Rita Cacace et al.   HUMAN MUTATION

Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD

(2015) Antonella Tramutola et al.   JOURNAL OF NEUROCHEMISTRY

Impact of Common Variations in PLD3 on Neuroimaging Phenotypes in Non-demented Elders

(2015) Chong Wang et al.   MOLECULAR NEUROBIOLOGY

PLD3 gene variants and Alzheimer's disease

(2015) Basavaraj V. Hooli et al.   NATURE

PLD3 and sporadic Alzheimer's disease risk

(2015) Jean-Charles Lambert et al.   NATURE

PLD3 in non-familial Alzheimer's disease

(2015) Stefanie Heilmann et al.   NATURE

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways

(2015) Alessandro Valli et al.   Oncotarget

Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease

(2014) Teng Jiang et al.   PHARMACOLOGICAL RESEARCH

PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains

(2014) Jun-ichi Satoh et al.   Alzheimers Research & Therapy

Targeting the mTOR Signaling Network for Alzheimer’s Disease Therapy

(2013) Chong Wang et al.   MOLECULAR NEUROBIOLOGY

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

Phospholipase D in brain function and Alzheimer's disease

(2010) Tiago Gil Oliveira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Phospholipase D in endocytosis and endosomal recycling pathways

(2009) Julie G. Donaldson   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS