Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing

Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes

(2017) Lauren E. Dalton et al.   MOLECULAR BIOLOGY OF THE CELL

PLD3 gene and processing of APP

(2017) Pietro Fazzari et al.   NATURE

Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

(2017) Reisuke H. Takahashi et al.   PATHOLOGY INTERNATIONAL

Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions

(2016) W. H. Toh et al.   BIOCHEMICAL JOURNAL

Coding mutations inSORL1and Alzheimer disease

(2015) Badri N. Vardarajan et al.   ANNALS OF NEUROLOGY

Retromer and sorting nexins in endosomal sorting

(2015) Matthew Gallon et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease

(2015) A Rovelet-Lecrux et al.   MOLECULAR PSYCHIATRY

PLD3 variants in population studies

(2015) Sven J. van der Lee et al.   NATURE

PLD3 gene variants and Alzheimer's disease

(2015) Basavaraj V. Hooli et al.   NATURE

PLD3 in non-familial Alzheimer's disease

(2015) Stefanie Heilmann et al.   NATURE

Retromer in Alzheimer disease, Parkinson disease and other neurological disorders

(2015) Scott A. Small et al.   NATURE REVIEWS NEUROSCIENCE

The Use of Pharmacological Retromer Chaperones in Alzheimer’s Disease and other Endosomal-related Disorders

(2014) Diego E. Berman et al.   Neurotherapeutics

Genome-wide RNAi Screen Reveals a Role for Multipass Membrane Proteins in Endosome-to-Golgi Retrieval

(2014) Sophia Y. Breusegem et al.   Cell Reports

Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity

(2014) Xin Wang et al.   Cell Reports

Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease

(2013) T. E. Willnow et al.   JOURNAL OF CELL SCIENCE

Extending the Mannose 6-Phosphate Glycoproteome by High Resolution/Accuracy Mass Spectrometry Analysis of Control and Acid Phosphatase 5-Deficient Mice

(2013) David E. Sleat et al.   MOLECULAR & CELLULAR PROTEOMICS

Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis

(2013) Sai Srinivas Panapakkam Giridharan et al.   MOLECULAR BIOLOGY OF THE CELL

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

The retromer complex - endosomal protein recycling and beyond

(2012) M. N. J. Seaman   JOURNAL OF CELL SCIENCE

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

(2012) A. W. Fjorback et al.   JOURNAL OF NEUROSCIENCE

Identification of Alzheimer disease-associated variants in genes that regulate retromer function

(2012) Badri N. Vardarajan et al.   NEUROBIOLOGY OF AGING

Retromers in Alzheimer’s Disease

(2012) Barbara M. Siegenthaler et al.   Neurodegenerative Diseases

Membrane Trafficking Pathways in Alzheimer's Disease

(2012) Lawrence Rajendran et al.   TRAFFIC

Mammalian phospholipase D physiological and pathological roles

(2011) X. Peng et al.   Acta Physiologica

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

MICAL-L1 Links EHD1 to Tubular Recycling Endosomes and Regulates Receptor Recycling

(2009) Mahak Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE