RFX1 downregulation contributes to TLR4 overexpression in CD14+ monocytes via epigenetic mechanisms in coronary artery disease

IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation

(2018) Ming Zhao et al.   Nature Communications

Epigenetic mechanisms in coronary artery disease: The current state and prospects

(2017) Lian Duan et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Soya-cerebroside, an extract of Cordyceps militaris, suppresses monocyte migration and prevents cartilage degradation in inflammatory animal models

(2017) Shan-Chi Liu et al.   Scientific Reports

DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice

(2016) Hua-Ping Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation

(2016) Qing-Peng Hu et al.   BMC NEUROSCIENCE

Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques

(2016) Anna Greißel et al.   CARDIOVASCULAR PATHOLOGY

Transcription factor RFX1 is ubiquitinated by E3 ligase STUB1 in systemic lupus erythematosus

(2016) Yu Guo et al.   CLINICAL IMMUNOLOGY

ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis

(2016) Godfrey S. Getz et al.   JOURNAL OF LIPID RESEARCH

miR-22 contributes to the pathogenesis of patients with coronary artery disease by targeting MCP-1

(2016) Bairong Chen et al.   MEDICINE

RFX1 maintains testis cord integrity by regulating the expression ofItga6in male mouse embryos

(2016) Bo Wang et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis

(2016) Shuo Geng et al.   Nature Communications

The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages

(2016) Rumi Hachiya et al.   Scientific Reports

A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts

(2016) Corinne Sidler et al.   Aging-US

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4

(2016) Yu Tina Zhao et al.   PLoS One

Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability

(2015) Simona Gargiulo et al.   AGING CELL

The Epigenetic Memory of Monocytes and Macrophages as a Novel Drug Target in Atherosclerosis

(2015) Siroon Bekkering et al.   CLINICAL THERAPEUTICS

Macrophage Differentiation from Monocytes Is Influenced by the Lipid Oxidation Degree of Low Density Lipoprotein

(2015) Jin-Won Seo et al.   MEDIATORS OF INFLAMMATION

RFX transcription factors are essential for hearing in mice

(2015) Ran Elkon et al.   Nature Communications

NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease

(2014) Lili Wang et al.   Archives of Medical Science

Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes

(2014) Siroon Bekkering et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Local carotid atherosclerotic plaque proteins for the identification of circulating biomarkers in coronary patients

(2014) Eric Malaud et al.   ATHEROSCLEROSIS

Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy

(2014) Min Xie et al.   CIRCULATION

Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients

(2014) Priyanka Sharma et al.   GENE

Relationship between toll-like receptor 4 levels in aorta and severity of atherosclerosis

(2014) Shanshan Xing et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma

(2014) C. Feng et al.   NEURO-ONCOLOGY

TLR4-Mediated Expression of Mac-1 in Monocytes Plays a Pivotal Role in Monocyte Adhesion to Vascular Endothelium

(2014) Seung Jin Lee et al.   PLoS One

TLR3 and TLR4 as potential clinically biomarkers of cardiovascular risk in coronary artery disease (CAD) patients

(2013) Liang Shao et al.   HEART AND VESSELS

TLR4 Signaling Augments Monocyte Chemotaxis by Regulating G Protein-Coupled Receptor Kinase 2 Translocation

(2013) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

Monocytes in Coronary Artery Disease and Atherosclerosis

(2013) Angie Ghattas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Role of Monocytes in Angiogenesis and Atherosclerosis

(2013) Anthony S. Jaipersad et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anti-CD14 antibody reduces LPS responsiveness via TLR4 internalization in human monocytes

(2013) Donghee Kim et al.   MOLECULAR IMMUNOLOGY

Peripheral Blood Monocyte Sirt1 Expression Is Reduced in Patients with Coronary Artery Disease

(2013) Alexander Breitenstein et al.   PLoS One

Regulatory Factor X1-induced Down-regulation of Transforming Growth Factor β2 Transcription in Human Neuroblastoma Cells

(2012) Chenzhuo Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic Modification of TLRs in Leukocytes Is Associated with Increased Susceptibility to Salmonella enteritidis in Chickens

(2012) Zhongyong Gou et al.   PLoS One

Myeloid related proteins activate Toll-like receptor 4 in human acute coronary syndromes

(2011) Keiko Yonekawa et al.   ATHEROSCLEROSIS

cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus

(2011) Thomas Rauen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1

(2011) Ming Zhao et al.   ARTHRITIS RESEARCH & THERAPY

Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells

(2010) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

Regulation ofFGF1Gene Promoter through Transcription Factor RFX1

(2010) Yi-Chao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll like receptor 4 in atherosclerosis and plaque destabilization

(2009) Wijnand K. den Dekker et al.   ATHEROSCLEROSIS

The monocyte/macrophage as a therapeutic target in atherosclerosis

(2009) Prakash Saha et al.   CURRENT OPINION IN PHARMACOLOGY

Epigenetic Regulation of TLR4 Gene Expression in Intestinal Epithelial Cells for the Maintenance of Intestinal Homeostasis

(2009) K. Takahashi et al.   JOURNAL OF IMMUNOLOGY

Identification and characterization of novel human tissue-specific RFX transcription factors

(2008) Syed Aftab et al.   BMC EVOLUTIONARY BIOLOGY

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

(2008) Anne Granger et al.   FASEB JOURNAL

Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness

(2007) A.H. Schoneveld et al.   ATHEROSCLEROSIS